| http://purl.uniprot.org/citations/3352637 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3352637 | http://www.w3.org/2000/01/rdf-schema#comment | "The induction of dominant cataract mutations by procarbazine was studied concomitantly with the induction of specific-locus mutations in treated male mice. The most effective dose in the specific-locus test, 600 mg/kg of procarbazine, and a fractionated dose of 5 X 200 mg/kg were used. The frequencies of dominant cataract mutations were higher, but not significantly different from the historical control. The ratio between the number of recovered specific-locus and dominant cataract mutations was in accordance with that found in our experiments with gamma-rays (Ehling et al., 1982; Kratochvilova, 1981) or in experiments with ethylnitrosourea (Favor, 1986). A total of 3 dominant cataract mutations were recovered in the offspring of procarbazine-treated spermatogonial stem cells. Two mutations had complete penetrance while the third exhibited a reduced penetrance of approximately 70%. The viability and fertility of the heterozygotes of all 3 mutations were not affected. Only 1 mutation was shown to be viable as a homozygote."xsd:string |
| http://purl.uniprot.org/citations/3352637 | http://purl.org/dc/terms/identifier | "doi:10.1016/0027-5107(88)90006-1"xsd:string |
| http://purl.uniprot.org/citations/3352637 | http://purl.uniprot.org/core/author | "Favor J."xsd:string |
| http://purl.uniprot.org/citations/3352637 | http://purl.uniprot.org/core/author | "Neuhauser-Klaus A."xsd:string |
| http://purl.uniprot.org/citations/3352637 | http://purl.uniprot.org/core/author | "Kratochvilova J."xsd:string |
| http://purl.uniprot.org/citations/3352637 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/3352637 | http://purl.uniprot.org/core/name | "Mutat Res"xsd:string |
| http://purl.uniprot.org/citations/3352637 | http://purl.uniprot.org/core/pages | "295-301"xsd:string |
| http://purl.uniprot.org/citations/3352637 | http://purl.uniprot.org/core/title | "Dominant cataract and recessive specific-locus mutations detected in offspring of procarbazine-treated male mice."xsd:string |
| http://purl.uniprot.org/citations/3352637 | http://purl.uniprot.org/core/volume | "198"xsd:string |
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