RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/33666217http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/33666217http://www.w3.org/2000/01/rdf-schema#comment"Phosphatidylinositol 3-kinases (PI3Ks) are critical regulators of many cellular processes including cell survival, proliferation, migration, cytoskeletal reorganization, and intracellular vesicular trafficking. They are a family of lipid kinases that phosphorylate membrane phosphoinositide lipids at the 3' position of their inositol rings, and in mammals they are divided into three classes. The role of the class III PI3K Vps34 is well-established, but recent evidence suggests the physiological significance of class II PI3K isoforms in vesicular trafficking. This review focuses on the recently discovered functions of the distinct PI3K-C2α and PI3K-C2β class II PI3K isoforms in clathrin-mediated endocytosis and consequent endosomal signaling, and discusses recently reported data on class II PI3K isoforms in different physiological contexts in comparison with class I and III isoforms."xsd:string
http://purl.uniprot.org/citations/33666217http://purl.org/dc/terms/identifier"doi:10.1042/bst20200835"xsd:string
http://purl.uniprot.org/citations/33666217http://purl.uniprot.org/core/author"Yoshioka K."xsd:string
http://purl.uniprot.org/citations/33666217http://purl.uniprot.org/core/date"2021"xsd:gYear
http://purl.uniprot.org/citations/33666217http://purl.uniprot.org/core/name"Biochem Soc Trans"xsd:string
http://purl.uniprot.org/citations/33666217http://purl.uniprot.org/core/pages"893-901"xsd:string
http://purl.uniprot.org/citations/33666217http://purl.uniprot.org/core/title"Class II phosphatidylinositol 3-kinase isoforms in vesicular trafficking."xsd:string
http://purl.uniprot.org/citations/33666217http://purl.uniprot.org/core/volume"49"xsd:string
http://purl.uniprot.org/citations/33666217http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/33666217
http://purl.uniprot.org/citations/33666217http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/33666217
http://purl.uniprot.org/uniprot/#_B7ZLY6-mappedCitation-33666217http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33666217
http://purl.uniprot.org/uniprot/#_O75747-mappedCitation-33666217http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33666217
http://purl.uniprot.org/uniprot/O75747http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/33666217
http://purl.uniprot.org/uniprot/B7ZLY6http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/33666217