| http://purl.uniprot.org/citations/33689881 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/33689881 | http://www.w3.org/2000/01/rdf-schema#comment | "Meiotic homologous recombination (HR) initiates with the programmed generation of DNA double-strand breaks (DSBs), which result in the exchange of genetic information and genome diversity. This process requires the tight cooperation of the MRE11-RAD50-NBS1 (MRN) complex to promote DSB formation and DNA end resection. However, the mechanism regulating MRN complex remains to be explored. In the present study, we report that MRN-interacting protein, MRNIP, is a novel factor for HR and is crucial for the expression of the MRN complex and loading of recombinases DMC1/RAD51. Knockout of Mrnip in mice led to aberrant synapsis, impaired HR, and male subfertility. In conclusion, MRNIP is a novel HR factor that probably promotes meiotic progression through the MRN complex."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2021.02.143"xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Huang X."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Liu S."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Lin M."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Wu Y."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Shen C."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Wang F."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Yu J."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Xu J."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Zhao D."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Zheng B."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Guan X."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/author | "Lv J."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/pages | "127-133"xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/title | "MRNIP is essential for meiotic progression and spermatogenesis in mice."xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://purl.uniprot.org/core/volume | "550"xsd:string |
| http://purl.uniprot.org/citations/33689881 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/33689881 |
| http://purl.uniprot.org/citations/33689881 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/33689881 |
| http://purl.uniprot.org/uniprot/#_F6S5X0-mappedCitation-33689881 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33689881 |
| http://purl.uniprot.org/uniprot/#_Q9D1F5-mappedCitation-33689881 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33689881 |