| http://purl.uniprot.org/citations/33692777 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/33692777 | http://www.w3.org/2000/01/rdf-schema#comment | "Extrahepatic cancers of the biliary system are typically asymptomatic until after metastasis, which contributes to their poor prognosis. Here we examined intrahepatic cholangiocarcinomas (n = 8), carcinomas of perihilar bile ducts (n = 7), carcinomas of the gallbladder (n = 11) and hepatic metastasis from carcinomas of the gallbladder (n = 4) for the expression of the extracellular matrix glycoproteins tenascin-C and tenascin-W. Anti-tenascin-C and anti-tenascin-W immunoreactivity was found in all biliary tract tumors examined. Unlike tenascin-C, tenascin-W was not detected in normal hepatobiliary tissue. Tenascin-W was also expressed by the cholangiocarcinoma-derived cell line Huh-28. However, co-culture of Huh-28 cells with immortalized bone marrow-derived stromal cells was necessary for the formation and organization of tenascin-W fibrils in vitro. Our results indicate that tenascin-W may be a novel marker of hepatobiliary tumor stroma, and its absence from many normal tissues suggests that it may be a potential target for biotherapies."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.org/dc/terms/identifier | "doi:10.3389/fimmu.2020.630139"xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Hess D."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Degen M."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Ruiz C."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Campo L."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Chiquet-Ehrismann R."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Tucker R.P."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Bichet S."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Terracciano L.M."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Hendaoui I."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Mebarki S."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Lahmar A."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Charrada-Ben Farhat L."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Hefaiedh R."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Hendaoui L."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/author | "Kchir N."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/name | "Front Immunol"xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/pages | "630139"xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/title | "Tenascin-W Is a Novel Stromal Marker in Biliary Tract Cancers."xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://purl.uniprot.org/core/volume | "11"xsd:string |
| http://purl.uniprot.org/citations/33692777 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/33692777 |
| http://purl.uniprot.org/citations/33692777 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/33692777 |