| http://purl.uniprot.org/citations/33769281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/33769281 | http://www.w3.org/2000/01/rdf-schema#comment | "Tissue organization is often characterized by specific patterns of cell morphology. How such patterns emerge in developing tissues is a fundamental open question. Here, we investigate the emergence of tissue-scale patterns of cell shape and mechanical tissue stress in the Drosophila wing imaginal disc during larval development. Using quantitative analysis of the cellular dynamics, we reveal a pattern of radially oriented cell rearrangements that is coupled to the buildup of tangential cell elongation. Developing a laser ablation method, we map tissue stresses and extract key parameters of tissue mechanics. We present a continuum theory showing that this pattern of cell morphology and tissue stress can arise via self-organization of a mechanical feedback that couples cell polarity to active cell rearrangements. The predictions of this model are supported by knockdown of MyoVI, a component of mechanosensitive feedback. Our work reveals a mechanism for the emergence of cellular patterns in morphogenesis."xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.org/dc/terms/identifier | "doi:10.7554/elife.57964"xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/author | "Dye N.A."xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/author | "Eaton S."xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/author | "Popovic M."xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/author | "Julicher F."xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/author | "Iyer K.V."xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/author | "Piscitello-Gomez R."xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/author | "Fuhrmann J.F."xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/name | "Elife"xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/pages | "e57964"xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/title | "Self-organized patterning of cell morphology via mechanosensitive feedback."xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/33769281 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/33769281 |
| http://purl.uniprot.org/citations/33769281 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/33769281 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LFK8-mappedCitation-33769281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33769281 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KGX1-mappedCitation-33769281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33769281 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LHV4-mappedCitation-33769281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33769281 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LGL8-mappedCitation-33769281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33769281 |
| http://purl.uniprot.org/uniprot/#_A1Z6W3-mappedCitation-33769281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33769281 |
| http://purl.uniprot.org/uniprot/#_A1ZAW0-mappedCitation-33769281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33769281 |
| http://purl.uniprot.org/uniprot/#_B7YZQ0-mappedCitation-33769281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33769281 |
| http://purl.uniprot.org/uniprot/#_B5RJR1-mappedCitation-33769281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33769281 |