http://purl.uniprot.org/citations/33798432 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/33798432 | http://www.w3.org/2000/01/rdf-schema#comment | "Animals respond to visual threats, such as a looming object, with innate defensive behaviors. Here, we report that a specific type of retinal ganglion cell (RGC), the OFF-transient alpha RGC, is critical for the detection of looming objects. We identified Kcnip2 as its molecular marker. The activity of the Kcnip2-expressing RGCs encodes the size of the looming object. Ablation or suppression of these RGCs abolished or severely impaired the escape and freezing behaviors of mice in response to a looming object, while activation of their somas in the retina, or their axon terminals in the superior colliculus, triggered immediate escape behavior. Our results link the activity of a single type of RGC to visually triggered innate defensive behaviors and underscore that ethologically significant visual information is encoded by a labeled line strategy as early as in the retina."xsd:string |
http://purl.uniprot.org/citations/33798432 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cub.2021.03.025"xsd:string |
http://purl.uniprot.org/citations/33798432 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
http://purl.uniprot.org/citations/33798432 | http://purl.uniprot.org/core/author | "Wang F."xsd:string |
http://purl.uniprot.org/citations/33798432 | http://purl.uniprot.org/core/author | "Wu Q."xsd:string |
http://purl.uniprot.org/citations/33798432 | http://purl.uniprot.org/core/author | "Li E."xsd:string |
http://purl.uniprot.org/citations/33798432 | http://purl.uniprot.org/core/author | "De L."xsd:string |
http://purl.uniprot.org/citations/33798432 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
http://purl.uniprot.org/citations/33798432 | http://purl.uniprot.org/core/name | "Curr Biol"xsd:string |
http://purl.uniprot.org/citations/33798432 | http://purl.uniprot.org/core/pages | "2263-2273.e3"xsd:string |
http://purl.uniprot.org/citations/33798432 | http://purl.uniprot.org/core/title | "OFF-transient alpha RGCs mediate looming triggered innate defensive response."xsd:string |
http://purl.uniprot.org/citations/33798432 | http://purl.uniprot.org/core/volume | "31"xsd:string |
http://purl.uniprot.org/citations/33798432 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/33798432 |
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