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http://purl.uniprot.org/citations/33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/33798432http://www.w3.org/2000/01/rdf-schema#comment"Animals respond to visual threats, such as a looming object, with innate defensive behaviors. Here, we report that a specific type of retinal ganglion cell (RGC), the OFF-transient alpha RGC, is critical for the detection of looming objects. We identified Kcnip2 as its molecular marker. The activity of the Kcnip2-expressing RGCs encodes the size of the looming object. Ablation or suppression of these RGCs abolished or severely impaired the escape and freezing behaviors of mice in response to a looming object, while activation of their somas in the retina, or their axon terminals in the superior colliculus, triggered immediate escape behavior. Our results link the activity of a single type of RGC to visually triggered innate defensive behaviors and underscore that ethologically significant visual information is encoded by a labeled line strategy as early as in the retina."xsd:string
http://purl.uniprot.org/citations/33798432http://purl.org/dc/terms/identifier"doi:10.1016/j.cub.2021.03.025"xsd:string
http://purl.uniprot.org/citations/33798432http://purl.uniprot.org/core/author"Zhang Y."xsd:string
http://purl.uniprot.org/citations/33798432http://purl.uniprot.org/core/author"Wang F."xsd:string
http://purl.uniprot.org/citations/33798432http://purl.uniprot.org/core/author"Wu Q."xsd:string
http://purl.uniprot.org/citations/33798432http://purl.uniprot.org/core/author"Li E."xsd:string
http://purl.uniprot.org/citations/33798432http://purl.uniprot.org/core/author"De L."xsd:string
http://purl.uniprot.org/citations/33798432http://purl.uniprot.org/core/date"2021"xsd:gYear
http://purl.uniprot.org/citations/33798432http://purl.uniprot.org/core/name"Curr Biol"xsd:string
http://purl.uniprot.org/citations/33798432http://purl.uniprot.org/core/pages"2263-2273.e3"xsd:string
http://purl.uniprot.org/citations/33798432http://purl.uniprot.org/core/title"OFF-transient alpha RGCs mediate looming triggered innate defensive response."xsd:string
http://purl.uniprot.org/citations/33798432http://purl.uniprot.org/core/volume"31"xsd:string
http://purl.uniprot.org/citations/33798432http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/33798432
http://purl.uniprot.org/citations/33798432http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/33798432
http://purl.uniprot.org/uniprot/#_A0A5F8MPB0-mappedCitation-33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33798432
http://purl.uniprot.org/uniprot/#_A0A2I3BPD4-mappedCitation-33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33798432
http://purl.uniprot.org/uniprot/#_A0A2I3BPY2-mappedCitation-33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33798432
http://purl.uniprot.org/uniprot/#_E0CX94-mappedCitation-33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33798432
http://purl.uniprot.org/uniprot/#_E0CXC0-mappedCitation-33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33798432
http://purl.uniprot.org/uniprot/#_E9QNK8-mappedCitation-33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33798432
http://purl.uniprot.org/uniprot/#_F7BWB2-mappedCitation-33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33798432
http://purl.uniprot.org/uniprot/#_F6TBA6-mappedCitation-33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33798432
http://purl.uniprot.org/uniprot/#_Q8BQN4-mappedCitation-33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33798432
http://purl.uniprot.org/uniprot/#_Q8BQV2-mappedCitation-33798432http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33798432