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http://purl.uniprot.org/citations/33844120http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/33844120http://www.w3.org/2000/01/rdf-schema#comment"Two Saccharomyces cerevisiae strains, BY4741 and BY4741-derived strain lacking the IST2 gene (ist2Δ), were used to characterise the possible role of cortical endoplasmic reticulum (ER) protein Ist2 upon cell dehydration and subsequent rehydration. For the first time, we show that not only protein components of the plasma membrane (PM), but also at least one ER membrane protein (Ist2) play an important role in the maintenance of the viability of yeast cells during dehydration and subsequent rehydration. The low viability of the mutant strain ist2∆ upon dehydration-rehydration stress was related to the lack of Ist2 protein in the ER. We revealed that the PM of ist2∆ strain is not able to completely restore its molecular organisation during reactivation from the state of anhydrobiosis. As the result, the permeability of the PM remains high regardless of the type of reactivation (rapid or gradual rehydration). We conclude that ER protein Ist2 plays an important role in ensuring the stability of molecular organisation and functionality of the PM during dehydration-rehydration stress. These results indicate an important role of ER-PM interactions during cells transition into the state of anhydrobiosis and the subsequent restoration of their physiological activities."xsd:string
http://purl.uniprot.org/citations/33844120http://purl.org/dc/terms/identifier"doi:10.1007/s10482-021-01578-8"xsd:string
http://purl.uniprot.org/citations/33844120http://purl.uniprot.org/core/author"Sychrova H."xsd:string
http://purl.uniprot.org/citations/33844120http://purl.uniprot.org/core/author"Papouskova K."xsd:string
http://purl.uniprot.org/citations/33844120http://purl.uniprot.org/core/author"Rapoport A."xsd:string
http://purl.uniprot.org/citations/33844120http://purl.uniprot.org/core/author"Dauss E."xsd:string
http://purl.uniprot.org/citations/33844120http://purl.uniprot.org/core/date"2021"xsd:gYear
http://purl.uniprot.org/citations/33844120http://purl.uniprot.org/core/name"Antonie Van Leeuwenhoek"xsd:string
http://purl.uniprot.org/citations/33844120http://purl.uniprot.org/core/pages"1069-1077"xsd:string
http://purl.uniprot.org/citations/33844120http://purl.uniprot.org/core/title"Anhydrobiosis in yeast: role of cortical endoplasmic reticulum protein Ist2 in Saccharomyces cerevisiae cells during dehydration and subsequent rehydration."xsd:string
http://purl.uniprot.org/citations/33844120http://purl.uniprot.org/core/volume"114"xsd:string
http://purl.uniprot.org/citations/33844120http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/33844120
http://purl.uniprot.org/citations/33844120http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/33844120
http://purl.uniprot.org/uniprot/#_A0A8H4BV72-mappedCitation-33844120http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33844120
http://purl.uniprot.org/uniprot/#_P38250-mappedCitation-33844120http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33844120
http://purl.uniprot.org/uniprot/A0A8H4BV72http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/33844120
http://purl.uniprot.org/uniprot/P38250http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/33844120