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http://purl.uniprot.org/citations/33871651http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/33871651http://www.w3.org/2000/01/rdf-schema#comment"Light functions as the primary environmental stimulus and brassinosteroids (BRs) as important endogenous growth regulators throughout the plant lifecycle. Photomorphogenesis involves a series of vital developmental processes that require the suppression of BR-mediated seedling growth, but the mechanism underlying the light-controlled regulation of the BR pathway remains unclear. Here, we reveal that nuclear factor YC proteins (NF-YCs) function as essential repressors of the BR pathway during light-controlled hypocotyl growth in Arabidopsis thaliana. In the light, NF-YCs inhibit BR biosynthesis by directly targeting the promoter of the BR biosynthesis gene BR6ox2 and repressing its transcription. NF-YCs also interact with BIN2, a critical repressor of BR signaling, and facilitate its stabilization by promoting its Tyr200 autophosphorylation, thus inhibiting the BR signaling pathway. Consistently, loss-of-function mutants of NF-YCs show etiolated growth and constitutive BR responses, even in the light. Our findings uncover a dual role of NF-YCs in repressing BR biosynthesis and signaling, providing mechanistic insights into how light antagonizes the BR pathway to ensure photomorphogenic growth in Arabidopsis."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.org/dc/terms/identifier"doi:10.1093/plcell/koab112"xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/author"Hu Y."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/author"Liu H."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/author"Liu X."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/author"Tang Y."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/author"Zhang W."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/author"Zhang C."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/author"Yang Y."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/author"Hou X."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/author"Cai J."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/date"2021"xsd:gYear
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/name"Plant Cell"xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/pages"2360-2374"xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/title"Arabidopsis NF-YCs play dual roles in repressing brassinosteroid biosynthesis and signaling during light-regulated hypocotyl elongation."xsd:string
http://purl.uniprot.org/citations/33871651http://purl.uniprot.org/core/volume"33"xsd:string
http://purl.uniprot.org/citations/33871651http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/33871651
http://purl.uniprot.org/citations/33871651http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/33871651
http://purl.uniprot.org/uniprot/#_A0A178VBI6-mappedCitation-33871651http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33871651
http://purl.uniprot.org/uniprot/#_F4K0T0-mappedCitation-33871651http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33871651
http://purl.uniprot.org/uniprot/#_A0A1I9LT77-mappedCitation-33871651http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33871651
http://purl.uniprot.org/uniprot/#_A0A1P8BB55-mappedCitation-33871651http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33871651
http://purl.uniprot.org/uniprot/#_A0A1P8B4R4-mappedCitation-33871651http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33871651
http://purl.uniprot.org/uniprot/#_B9DFS3-mappedCitation-33871651http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33871651