http://purl.uniprot.org/citations/33909998 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/33909998 | http://www.w3.org/2000/01/rdf-schema#comment | "The Drosophila type II neuroblast lineages present an attractive model to investigate the neurogenesis and differentiation process as they adapt to a process similar to that in the human outer subventricular zone. We perform targeted single-cell mRNA sequencing in third instar larval brains to study this process of the type II NB lineage. Combining prior knowledge, in silico analyses, and in situ validation, our multi-informatic investigation describes the molecular landscape from a single developmental snapshot. 17 markers are identified to differentiate distinct maturation stages. 30 markers are identified to specify the stem cell origin and/or cell division numbers of INPs, and at least 12 neuronal subtypes are identified. To foster future discoveries, we provide annotated tables of pairwise gene-gene correlation in single cells and MiCV, a web tool for interactively analyzing scRNA-seq datasets. Taken together, these resources advance our understanding of the neural differentiation process at the molecular level."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.celrep.2021.109039"xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/author | "Lee C.Y."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/author | "Zhao Y."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/author | "Cao W."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/author | "Cai D."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/author | "Walker L.A."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/author | "Shen F.Y."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/author | "Michki N.S."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/author | "Sanjasaz K."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/name | "Cell Rep"xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/pages | "109039"xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/title | "The molecular landscape of neural differentiation in the developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis."xsd:string |
http://purl.uniprot.org/citations/33909998 | http://purl.uniprot.org/core/volume | "35"xsd:string |
http://purl.uniprot.org/citations/33909998 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/33909998 |
http://purl.uniprot.org/citations/33909998 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/33909998 |
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http://purl.uniprot.org/uniprot/#_A0A0B4KI24-mappedCitation-33909998 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33909998 |