| http://purl.uniprot.org/citations/33945787 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/33945787 | http://www.w3.org/2000/01/rdf-schema#comment | "Natural killer (NK) cells and type 1 innate lymphoid cells (ILC1s) are heterogenous innate lymphocytes broadly defined in mice as Lin-NK1.1+NKp46+ cells that express the transcription factor T-BET and produce interferon-γ. The ILC1 definition primarily stems from studies on liver and small intestinal populations. However, NK1.1+NKp46+ cells in the salivary glands, uterus, adipose, and other tissues exhibit nonuniform programs that differ from those of liver or intestinal ILC1s or NK cells. Here, we performed single-cell RNA sequencing on murine NK1.1+NKp46+ cells from blood, spleen, various tissues, and solid tumors. We identified gene expression programs of tissue-specific ILC1s, tissue-specific NK cells, and non-tissue-specific populations in blood, spleen, and other tissues largely corresponding to circulating cells. Moreover, we found that circulating NK cell programs were reshaped in tumor-bearing mice. Core programs of circulating and tumor NK cells paralleled conserved human NK cells signatures, advancing our understanding of the human NK-ILC1 spectrum."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.immuni.2021.03.024"xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Wang S.Y."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "David E."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Colonna M."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Cortez V.S."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Miller H.L."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Faccio R."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Amit I."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Ricci B."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Peng V."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Sudan R."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "McFarland A.P."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Landsberger T."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/author | "Yalin A."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/pages | "1320-1337.e4"xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/title | "Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation."xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://purl.uniprot.org/core/volume | "54"xsd:string |
| http://purl.uniprot.org/citations/33945787 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/33945787 |
| http://purl.uniprot.org/citations/33945787 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/33945787 |
| http://purl.uniprot.org/uniprot/#_A0A0U1RP63-mappedCitation-33945787 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33945787 |
| http://purl.uniprot.org/uniprot/#_A0A1B0GQX5-mappedCitation-33945787 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33945787 |