http://purl.uniprot.org/citations/33966694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/33966694 | http://www.w3.org/2000/01/rdf-schema#comment | "Objective To investigate the expression of Cripto-1 in pancreatic cancer and to analyze its clinical significance. Methods Cripto-1 expression in normal pancreas,pancreatic cancer and adjacent non-tumor tissues,chronic pancreatitis tissues and other related tissues was evaluated using immunohistochemistry.The association of Cripto-1 expression with the clinicopathological characteristics and the prognostic value of Cripto-1 in patients with pancreatic cancer were analyzed. Results The expression of Cripto-1 was higher in chronic pancreatitis tissues,pancreatic cancer and its metastases than in normal pancreas(P=0.019,P=0.025,and P=0.018,respectively).Cripto-1 overexpression was correlated with poorly differentiated pancreatic cancer.The patients with Cripto-1 upregulation had shorter median survival time(8 months vs.16 months,χ 2=4.787,P=0.029).However,multivariate analysis failed to demonstrate overexpression of Cripto-1 an independent prognostic indicator in patients with pancreatic cancer(HR=1.341,95% CI=0.800-2.248,P=0.266).Conclusions Cripto-1 may play an important role in the development and progression of pancreatic cancer.It can be a potential prognostic biomarker for patients with pancreatic cancer."xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.org/dc/terms/identifier | "doi:10.3881/j.issn.1000-503x.12734"xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/author | "Gao X."xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/author | "Lu T."xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/author | "Xu Q."xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/author | "Liao Q."xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/author | "Zhang R.H."xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/author | "Pan B.J."xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/name | "Zhongguo Yi Xue Ke Xue Yuan Xue Bao"xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/pages | "173-179"xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/title | "[Expression and Prognostic Value of Cripto-1 in Pancreatic Cancer]."xsd:string |
http://purl.uniprot.org/citations/33966694 | http://purl.uniprot.org/core/volume | "43"xsd:string |
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http://purl.uniprot.org/uniprot/F5H1T8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/33966694 |