RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/33979096http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/33979096http://www.w3.org/2000/01/rdf-schema#comment"Psoriasis is a chronic immune-mediated inflammatory skin disease, affects about 2% to 3% of the world population. Valosin-containing protein (VCP) is one of the newly discovered markers that is highly expressed in neoplasms and hyperproliferative lesions. This work aimed to study the role of VCP in psoriasis vulgaris by immunohistochemical study and correlate its expression with the available clinicopathologic data. This prospective case-control study was conducted on 25 patients with psoriasis vulgaris and 25 age-matched and sex-matched healthy individuals as a control group. Skin biopsies were taken under local anesthesia from cases and controls. VCP immunoreactivity showed that epidermal VCP expression had a significant stepwise increase (P=0.002) from control to lesional psoriatic sections. Epidermal VCP H-score was significantly associated with the progressive course (P=0.037). Similarly, VCP in the dermis showed a significant expression in lesional psoriatic skin (P≤0.001). Higher VCP in the dermis in cases with a history of joint affection (P<0.05) was detected. We concluded that VCP is a promising marker for follow-up and monitoring of psoriatic patients and may play a role as a therapeutic target."xsd:string
http://purl.uniprot.org/citations/33979096http://purl.org/dc/terms/identifier"doi:10.1097/pai.0000000000000944"xsd:string
http://purl.uniprot.org/citations/33979096http://purl.uniprot.org/core/author"Hagag M.M."xsd:string
http://purl.uniprot.org/citations/33979096http://purl.uniprot.org/core/author"Shehata W.A."xsd:string
http://purl.uniprot.org/citations/33979096http://purl.uniprot.org/core/author"El Dein Mohamed A.S."xsd:string
http://purl.uniprot.org/citations/33979096http://purl.uniprot.org/core/author"Kassem N.M.A.E."xsd:string
http://purl.uniprot.org/citations/33979096http://purl.uniprot.org/core/date"2021"xsd:gYear
http://purl.uniprot.org/citations/33979096http://purl.uniprot.org/core/name"Appl Immunohistochem Mol Morphol"xsd:string
http://purl.uniprot.org/citations/33979096http://purl.uniprot.org/core/pages"e68-e72"xsd:string
http://purl.uniprot.org/citations/33979096http://purl.uniprot.org/core/title"Valosin-containing Protein in Psoriasis: A Clinical and Immunohistochemical Study."xsd:string
http://purl.uniprot.org/citations/33979096http://purl.uniprot.org/core/volume"29"xsd:string
http://purl.uniprot.org/citations/33979096http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/33979096
http://purl.uniprot.org/citations/33979096http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/33979096
http://purl.uniprot.org/uniprot/#_Q0IIN5-mappedCitation-33979096http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33979096
http://purl.uniprot.org/uniprot/#_P55072-mappedCitation-33979096http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33979096
http://purl.uniprot.org/uniprot/#_Q96IF9-mappedCitation-33979096http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33979096
http://purl.uniprot.org/uniprot/#_Q9HAP0-mappedCitation-33979096http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33979096
http://purl.uniprot.org/uniprot/#_Q9HAP1-mappedCitation-33979096http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33979096
http://purl.uniprot.org/uniprot/#_Q9NTC4-mappedCitation-33979096http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33979096
http://purl.uniprot.org/uniprot/Q0IIN5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/33979096
http://purl.uniprot.org/uniprot/Q9NTC4http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/33979096
http://purl.uniprot.org/uniprot/P55072http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/33979096
http://purl.uniprot.org/uniprot/Q96IF9http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/33979096
http://purl.uniprot.org/uniprot/Q9HAP0http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/33979096