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http://purl.uniprot.org/citations/34004146http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/34004146http://www.w3.org/2000/01/rdf-schema#comment"The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in perception, cognition, emotion, and learning. We profiled ∼1.3 million cells covering the entire adult mouse isocortex and HPF and derived a transcriptomic cell-type taxonomy revealing a comprehensive repertoire of glutamatergic and GABAergic neuron types. Contrary to the traditional view of HPF as having a simpler cellular organization, we discover a complete set of glutamatergic types in HPF homologous to all major subclasses found in the six-layered isocortex, suggesting that HPF and the isocortex share a common circuit organization. We also identify large-scale continuous and graded variations of cell types along isocortical depth, across the isocortical sheet, and in multiple dimensions in hippocampus and subiculum. Overall, our study establishes a molecular architecture of the mammalian isocortex and hippocampal formation and begins to shed light on its underlying relationship with the development, evolution, connectivity, and function of these two brain structures."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.org/dc/terms/identifier"doi:10.1016/j.cell.2021.04.021"xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Lee C."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Ren Q."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Smith K.A."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Yao Z."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Zeng H."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Nguyen T.N."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Gray J."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Pham T."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Ward K."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"McMillen D."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Ding S.L."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Mok S."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Kroll M."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Tung H."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Tasic B."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Chiang M."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Sunkin S.M."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Levi B."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Dee N."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Gouwens N.W."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Sulc J."xsd:string
http://purl.uniprot.org/citations/34004146http://purl.uniprot.org/core/author"Hawrylycz M.J."xsd:string