| http://purl.uniprot.org/citations/34027651 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34027651 | http://www.w3.org/2000/01/rdf-schema#comment | "Recently, Up-frameshift protein 1 (UPF1) is reported to be downregulated in various cancers and its low expression is closely correlated with poor prognosis. UPF1 is well known as a master regulator of nonsense-mediated mRNA decay (NMD), which serves as a highly conserved mRNA surveillance process protecting cells from aberrant toxic transcripts. Due to dysfunction of UPF1, NMD fails to proceed, which contributes to tumor initiation and progression. This review shows a brief summary of the aberrant expression, functional roles and molecular mechanisms of UPF1 during tumorigenesis. Increasing evidence has indicated that UPF1 could serve as a potential biomarker for cancer diagnosis and treatment for future clinical applications in cancer."xsd:string |
| http://purl.uniprot.org/citations/34027651 | http://purl.org/dc/terms/identifier | "doi:10.52586/4925"xsd:string |
| http://purl.uniprot.org/citations/34027651 | http://purl.uniprot.org/core/author | "Chen B.L."xsd:string |
| http://purl.uniprot.org/citations/34027651 | http://purl.uniprot.org/core/author | "Wang H.M."xsd:string |
| http://purl.uniprot.org/citations/34027651 | http://purl.uniprot.org/core/author | "Lin X.S."xsd:string |
| http://purl.uniprot.org/citations/34027651 | http://purl.uniprot.org/core/author | "Zeng Y.M."xsd:string |
| http://purl.uniprot.org/citations/34027651 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34027651 | http://purl.uniprot.org/core/name | "Front Biosci (Landmark Ed)"xsd:string |
| http://purl.uniprot.org/citations/34027651 | http://purl.uniprot.org/core/pages | "76-84"xsd:string |
| http://purl.uniprot.org/citations/34027651 | http://purl.uniprot.org/core/title | "UPF1: a potential biomarker in human cancers."xsd:string |
| http://purl.uniprot.org/citations/34027651 | http://purl.uniprot.org/core/volume | "26"xsd:string |
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