| http://purl.uniprot.org/citations/34052659 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34052659 | http://www.w3.org/2000/01/rdf-schema#comment | "We recently isolated a novel co-activator of peroxisome proliferator-activated receptor γ, helicase with zinc finger 2 (HELZ2). HELZ2 null mice were resistant to diet-induced obesity and NAFFL/NASH, and HELZ2 was phosphorylated at tyrosine residues. In order to find a factor related to HELZ2, we analyzed products co-immunoprecipitated with phosphorylated HELZ2 by mass spectrometry analyses. We identified proline- and glutamine-rich (SFPQ) as a protein associating with tyrosine-phosphorylated HELZ2. The knockdown of SFPQ in 3T3-L1 cells downregulated mRNA levels of transcription factors including Krox20, Cebpβ, and Cebpδ: key factors for early-stage adipocyte differentiation. In addition, knockdown of SFPQ inhibited 3T3-L1 cell differentiation to mature adipocytes. These findings demonstrated that SFPQ associating with HELZ2 is an important novel transcriptional regulator of adipocyte differentiation."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2021.05.014"xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Nakajima Y."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Saito T."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Yamada M."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Satoh T."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Yoshino S."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Ozawa A."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Tomaru T."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Katano-Toki A."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Horiguchi K."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Ishida E."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/author | "Nishikido A."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/pages | "139-145"xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/title | "SFPQ associated with a co-activator for PPARgamma, HELZ2, regulates key nuclear factors for adipocyte differentiation."xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://purl.uniprot.org/core/volume | "562"xsd:string |
| http://purl.uniprot.org/citations/34052659 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34052659 |
| http://purl.uniprot.org/citations/34052659 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34052659 |
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| http://purl.uniprot.org/uniprot/#_Q3TZD5-mappedCitation-34052659 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34052659 |
| http://purl.uniprot.org/uniprot/#_Q3TZL2-mappedCitation-34052659 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34052659 |