| http://purl.uniprot.org/citations/34067415 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34067415 | http://www.w3.org/2000/01/rdf-schema#comment | "Studies of the function of the female reproductive system in zero gravity are urgent for the future exploration of deep space. Female reproductive cells, oocytes, are rich in mitochondria, which allow oocytes to produce embryos. The rate of cellular respiration was determined to assess the functional state of the mitochondrial apparatus in Drosophila melanogaster ovaries in which the full cycle of oogenesis took place under simulated microgravity. Since cellular respiration depends on the state of the cytoskeleton, the contents of the main cytoskeletal proteins were determined by Western blotting. To modulate the structure of the cytoskeleton, essential phospholipids were administered per os at a dosage of 500 mg/kg in medium. The results of this study show that after a full cycle of oogenesis under simulated microgravity, the rate of cellular respiration in the fruit fly ovaries increases, apparently due to complex II of the respiratory chain. At the same time, we did not find any changes in the area of oocytes or in the content of proteins in the respiratory chain. However, changes were found in the relative contents of proteins of the actin cytoskeleton. There were no changes of essential phospholipids and no increase in the rate of cellular respiration of the ovaries after exposure to simulated microgravity. However, in the control, the administration of essential phospholipids led to a decrease in the efficiency of oxygen consumption in the flies' ovaries due to complexes IV-V."xsd:string |
| http://purl.uniprot.org/citations/34067415 | http://purl.org/dc/terms/identifier | "doi:10.3390/cimb43010015"xsd:string |
| http://purl.uniprot.org/citations/34067415 | http://purl.uniprot.org/core/author | "Ogneva I.V."xsd:string |
| http://purl.uniprot.org/citations/34067415 | http://purl.uniprot.org/core/author | "Usik M.A."xsd:string |
| http://purl.uniprot.org/citations/34067415 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34067415 | http://purl.uniprot.org/core/name | "Curr Issues Mol Biol"xsd:string |
| http://purl.uniprot.org/citations/34067415 | http://purl.uniprot.org/core/pages | "176-186"xsd:string |
| http://purl.uniprot.org/citations/34067415 | http://purl.uniprot.org/core/title | "Mitochondrial Respiration in Drosophila Ovaries after a Full Cycle of Oogenesis under Simulated Microgravity."xsd:string |
| http://purl.uniprot.org/citations/34067415 | http://purl.uniprot.org/core/volume | "43"xsd:string |
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