http://purl.uniprot.org/citations/34088631 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/34088631 | http://www.w3.org/2000/01/rdf-schema#comment | "Stomatin-like protein-2 (SLP-2) is a mitochondrial-associated protein that is abundant in cardiomyocytes. Many reports have shown that SLP-2 plays an important role in mitochondria. The treatment of mitochondrial cardiomyopathy (MCM) needs further improvement, so the relationship between SLP-2 and MCM is worth exploring. This study reviewed some protective mechanisms of SLP-2 on mitochondria. Published studies have shown that SLP-2 protects mitochondria by stabilising the function of optic atrophy 1 (OPA1), promoting mitofusin (Mfn) 2 expression, interacting with prohibitins and cardiolipin, forming SLP-2-PARL-YME1L (SPY) complex, and stabilising respiratory chain complexes, suggesting that SLP-2 is a new potential target for the treatment of MCM. However, the specific mechanism of SLP-2 needs to be confirmed by further research."xsd:string |
http://purl.uniprot.org/citations/34088631 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.hlc.2021.05.074"xsd:string |
http://purl.uniprot.org/citations/34088631 | http://purl.uniprot.org/core/author | "Chen W."xsd:string |
http://purl.uniprot.org/citations/34088631 | http://purl.uniprot.org/core/author | "Hu Y."xsd:string |
http://purl.uniprot.org/citations/34088631 | http://purl.uniprot.org/core/author | "Xu Y."xsd:string |
http://purl.uniprot.org/citations/34088631 | http://purl.uniprot.org/core/author | "Qiu Z."xsd:string |
http://purl.uniprot.org/citations/34088631 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
http://purl.uniprot.org/citations/34088631 | http://purl.uniprot.org/core/name | "Heart Lung Circ"xsd:string |
http://purl.uniprot.org/citations/34088631 | http://purl.uniprot.org/core/pages | "1449-1455"xsd:string |
http://purl.uniprot.org/citations/34088631 | http://purl.uniprot.org/core/title | "Stomatin-Like Protein-2: A Potential Target to Treat Mitochondrial Cardiomyopathy."xsd:string |
http://purl.uniprot.org/citations/34088631 | http://purl.uniprot.org/core/volume | "30"xsd:string |
http://purl.uniprot.org/citations/34088631 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34088631 |
http://purl.uniprot.org/citations/34088631 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34088631 |
http://purl.uniprot.org/uniprot/#_A0A087WYB4-mappedCitation-34088631 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34088631 |
http://purl.uniprot.org/uniprot/#_Q6ZNW0-mappedCitation-34088631 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34088631 |
http://purl.uniprot.org/uniprot/#_Q9UJZ1-mappedCitation-34088631 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34088631 |
http://purl.uniprot.org/uniprot/Q6ZNW0 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/34088631 |
http://purl.uniprot.org/uniprot/A0A087WYB4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/34088631 |
http://purl.uniprot.org/uniprot/Q9UJZ1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/34088631 |