http://purl.uniprot.org/citations/3409321 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3409321 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3409321 | http://www.w3.org/2000/01/rdf-schema#comment | "Expression of the interferon-beta (IFN-beta) gene is induced by a variety of agents, including viruses. Evidence has been provided that a mouse nuclear factor, termed interferon regulatory factor-1 (IRF-1), specifically binds to the upstream regulatory region of the human IFN-beta gene and mediates virus-induced transcription of the gene. In this study, we describe the molecular cloning and characterization of the mouse and human cDNAs encoding IRF-1. Our results suggest that IRF-1 is also involved in the regulation of other genes such as IFN-alpha and MHC class I genes. Surprisingly, IRF-1 gene expression is dramatically induced by Newcastle disease virus in mouse L929 cells and by Concanavalin A in spleen cells. We show here that the IRF-1 gene possesses virus-inducible promoter."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(88)91307-4"xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(88)91307-4"xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Kimura Y."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Kimura Y."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Miyata T."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Miyata T."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Fujita T."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Fujita T."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Sudo Y."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Sudo Y."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Taniguchi T."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Taniguchi T."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Miyamoto M."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Miyamoto M."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Maruyama M."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Maruyama M."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Harada H."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/author | "Harada H."xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/3409321 | http://purl.uniprot.org/core/name | "Cell"xsd:string |