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http://purl.uniprot.org/citations/3409321http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3409321http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3409321http://www.w3.org/2000/01/rdf-schema#comment"Expression of the interferon-beta (IFN-beta) gene is induced by a variety of agents, including viruses. Evidence has been provided that a mouse nuclear factor, termed interferon regulatory factor-1 (IRF-1), specifically binds to the upstream regulatory region of the human IFN-beta gene and mediates virus-induced transcription of the gene. In this study, we describe the molecular cloning and characterization of the mouse and human cDNAs encoding IRF-1. Our results suggest that IRF-1 is also involved in the regulation of other genes such as IFN-alpha and MHC class I genes. Surprisingly, IRF-1 gene expression is dramatically induced by Newcastle disease virus in mouse L929 cells and by Concanavalin A in spleen cells. We show here that the IRF-1 gene possesses virus-inducible promoter."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(88)91307-4"xsd:string
http://purl.uniprot.org/citations/3409321http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(88)91307-4"xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Kimura Y."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Kimura Y."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Miyata T."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Miyata T."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Fujita T."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Fujita T."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Sudo Y."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Sudo Y."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Taniguchi T."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Taniguchi T."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Miyamoto M."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Miyamoto M."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Maruyama M."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Maruyama M."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Harada H."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/author"Harada H."xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/date"1988"xsd:gYear
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/date"1988"xsd:gYear
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/3409321http://purl.uniprot.org/core/name"Cell"xsd:string