| http://purl.uniprot.org/citations/34109579 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34109579 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveThis meta-analysis aimed to assess the association of MUC-2 expression with clinicopathological parameters in gastric carcinoma (GC) patients.Materials and methodsClinical databases based on the study aim were searched in detail. The relative risk ratios (RRs) and associated 95% confidence intervals (95% CIs) were computed after eligible trials were included in the study.ResultsNineteen trials involving 2,363 GC patients were included in this meta-analysis. The expression of MUC-2 showed correlation with clinical stage (I/II vs. III/IV) (RR = 1.09, 95% CI: 1.00-1.18, I2 = 24%, p = 0.194), and lymphatic invasion (present vs. absent) (RR = 0.83, 95% CI: 0.72-0.95, I2 = 22.3%, p = 0.252). However, no significant association was identified between the MUC-2 expression and other clinicopathological parameters, including gender (male vs. female), tumor size (>5 vs. ≤5 cm), Lauren's classification (intestinal vs. diffuse), tumor differentiation (poorly vs. well and moderately), lymph node metastasis (present vs. absent), vascular invasion (present vs. absent), and 5-year survival (yes vs. no) of GC patients.ConclusionsOur meta-analysis findings suggested that MUC-2 positive cases were correlated with lower tumor stage and lower rate of lymphatic invasion. Further clinical studies are warranted to confirm the role of MUC-2 in clinical practice."xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.org/dc/terms/identifier | "doi:10.26355/eurrev_202105_25936"xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/author | "Wang H."xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/author | "Xu T."xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/author | "Su W."xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/author | "Yu M.H."xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/author | "Guo X.Z."xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/author | "Hu L.N."xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/name | "Eur Rev Med Pharmacol Sci"xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/pages | "3700-3708"xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/title | "Prognostic role of MUC-2 expression in patients with gastric carcinoma: a systematic review and meta-analysis."xsd:string |
| http://purl.uniprot.org/citations/34109579 | http://purl.uniprot.org/core/volume | "25"xsd:string |
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