| http://purl.uniprot.org/citations/3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/3422494 | http://www.w3.org/2000/01/rdf-schema#comment | "An enzyme activity capable of degrading the glycosyl-phosphatidylinositol membrane anchor of cell-surface proteins has previously been reported in a number of mammalian tissues. The experiments reported here demonstrate that this anchor-degrading activity is also abundant in mammalian plasma. The activity was inhibited by EGTA or 1,10-phenanthroline. It was capable of removing the anchor from alkaline phosphatase, 5'-nucleotidase, and variant surface glycoprotein but had little or not activity toward phosphatidylinositol or phosphatidylcholine. Phosphatidic acid was the only 3H-labeled product when this enzyme hydrolyzed [3H]myristate-labeled variant surface glycoprotein. It could be distinguished from the Ca2+-dependent inositol phospholipid-specific phospholipase C activity in several rat tissues on the basis of its molecular size and its sensitivity to 1,10-phenanthroline. The data therefore suggest that this activity is due to a phospholipase D with specificity for glycosyl-phosphatidylinositol structures. Although the precise physiological function of this anchor-specific phospholipase D remains to be determined, these findings indicate that it could play an important role in regulating the expression and release of cell-surface proteins in vivo."xsd:string |
| http://purl.uniprot.org/citations/3422494 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.85.4.980"xsd:string |
| http://purl.uniprot.org/citations/3422494 | http://purl.uniprot.org/core/author | "Low M.G."xsd:string |
| http://purl.uniprot.org/citations/3422494 | http://purl.uniprot.org/core/author | "Prasad A.R."xsd:string |
| http://purl.uniprot.org/citations/3422494 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/3422494 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/3422494 | http://purl.uniprot.org/core/pages | "980-984"xsd:string |
| http://purl.uniprot.org/citations/3422494 | http://purl.uniprot.org/core/title | "A phospholipase D specific for the phosphatidylinositol anchor of cell-surface proteins is abundant in plasma."xsd:string |
| http://purl.uniprot.org/citations/3422494 | http://purl.uniprot.org/core/volume | "85"xsd:string |
| http://purl.uniprot.org/citations/3422494 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3422494 |
| http://purl.uniprot.org/citations/3422494 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3422494 |
| http://purl.uniprot.org/citations/3422494 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3422494 |
| http://purl.uniprot.org/citations/3422494 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3422494 |
| http://purl.uniprot.org/enzyme/3.1.4.50 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/3422494 |
| http://purl.uniprot.org/uniprot/#_Q14210-mappedCitation-3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3422494 |
| http://purl.uniprot.org/uniprot/#_A6ND01-mappedCitation-3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3422494 |
| http://purl.uniprot.org/uniprot/#_P04216-mappedCitation-3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3422494 |
| http://purl.uniprot.org/uniprot/#_P09923-mappedCitation-3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3422494 |
| http://purl.uniprot.org/uniprot/#_Q10588-mappedCitation-3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3422494 |
| http://purl.uniprot.org/uniprot/#_Q14982-mappedCitation-3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3422494 |
| http://purl.uniprot.org/uniprot/#_O95274-mappedCitation-3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3422494 |
| http://purl.uniprot.org/uniprot/#_O95497-mappedCitation-3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3422494 |
| http://purl.uniprot.org/uniprot/#_O95498-mappedCitation-3422494 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3422494 |