| http://purl.uniprot.org/citations/34285221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34285221 | http://www.w3.org/2000/01/rdf-schema#comment | "The decline of neuronal synapses is an established feature of ageing accompanied by the diminishment of neuronal function, and in the motor system at least, a reduction of behavioural capacity. Here, we have investigated Drosophila motor neuron synaptic terminals during ageing. We observed cumulative fragmentation of presynaptic structures accompanied by diminishment of both evoked and miniature neurotransmission occurring in tandem with reduced motor ability. Through discrete manipulation of each neurotransmission modality, we find that miniature but not evoked neurotransmission is required to maintain presynaptic architecture and that increasing miniature events can both preserve synaptic structures and prolong motor ability during ageing. Our results establish that miniature neurotransmission, formerly viewed as an epiphenomenon, is necessary for the long-term stability of synaptic connections."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-021-24490-1"xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/author | "Jiao W."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/author | "Banerjee S."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/author | "Stowers R.S."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/author | "McCabe B.D."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/author | "Choi B.J."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/author | "Vernon S."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/author | "Ruchti E."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/author | "Asadzadeh J."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/author | "Burri O."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/pages | "4399"xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/title | "Miniature neurotransmission is required to maintain Drosophila synaptic structures during ageing."xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/34285221 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34285221 |
| http://purl.uniprot.org/citations/34285221 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34285221 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KG19-mappedCitation-34285221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34285221 |
| http://purl.uniprot.org/uniprot/#_B7Z0Z2-mappedCitation-34285221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34285221 |
| http://purl.uniprot.org/uniprot/#_M9MSE4-mappedCitation-34285221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34285221 |
| http://purl.uniprot.org/uniprot/#_M9MSE6-mappedCitation-34285221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34285221 |
| http://purl.uniprot.org/uniprot/#_M9MSE7-mappedCitation-34285221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34285221 |
| http://purl.uniprot.org/uniprot/#_M9MSE9-mappedCitation-34285221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34285221 |