| http://purl.uniprot.org/citations/3428594 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3428594 | http://www.w3.org/2000/01/rdf-schema#comment | "Previous studies showed that the mouse Elo (eye lens obsolescence) mutation is located on chromosome 1, at a site near the Len-1 locus, which is defined by a set of polymorphic gamma-crystallin proteins. To investigate further the relationship between Elo and the gamma-crystallins, we have examined the steady-state levels of gamma-crystallin transcripts in normal and mutant eyes and analyzed the linkage relationship between the Elo locus and the gamma-crystallin genes. Our data showed that, while gamma-crystallin mRNA levels are preferentially reduced in the mutant eyes, the mutation does not seem to map within the gamma-crystallin gene cluster. The distance between Elo and the gamma 6 gene (the most proximal gamma-crystallin gene member) is estimated to be 1.4 +/-0.9 cM, whereas that between gamma 6 and the distantly linked gamma 2 gene is 2.7 +/-1.3 cM. Our data also suggest the possibility of recombination hot spots with the gamma-crystallin gene cluster."xsd:string |
| http://purl.uniprot.org/citations/3428594 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.1.7.637"xsd:string |
| http://purl.uniprot.org/citations/3428594 | http://purl.uniprot.org/core/author | "Oda S."xsd:string |
| http://purl.uniprot.org/citations/3428594 | http://purl.uniprot.org/core/author | "Tsui L.C."xsd:string |
| http://purl.uniprot.org/citations/3428594 | http://purl.uniprot.org/core/author | "Breitman M.L."xsd:string |
| http://purl.uniprot.org/citations/3428594 | http://purl.uniprot.org/core/author | "Quinlan P."xsd:string |
| http://purl.uniprot.org/citations/3428594 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
| http://purl.uniprot.org/citations/3428594 | http://purl.uniprot.org/core/name | "Genes Dev"xsd:string |
| http://purl.uniprot.org/citations/3428594 | http://purl.uniprot.org/core/pages | "637-644"xsd:string |
| http://purl.uniprot.org/citations/3428594 | http://purl.uniprot.org/core/title | "The mouse eye lens obsolescence (Elo) mutant: studies on crystallin gene expression and linkage analysis between the mutant locus and the gamma-crystallin genes."xsd:string |
| http://purl.uniprot.org/citations/3428594 | http://purl.uniprot.org/core/volume | "1"xsd:string |
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