| http://purl.uniprot.org/citations/34294729 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34294729 | http://www.w3.org/2000/01/rdf-schema#comment | "This study aimed to investigate alterations in the activity and sleep of Drosophila melanogaster under simulated microgravity, which was implemented through the random positioning machine, while different light conditions (normal photoperiod and constant dark) were set. Fruit flies of different strains and sexes were treated for 3 days, and activity and sleep were monitored using the Drosophila Activity Monitoring System. After 3 days of treatment, fruit flies were sampled to detect the relative expression levels of the major clock genes and some neurotransmitter-related genes. The results showed that for the normal photoperiod (LD) condition, the activity increased and sleep decreased under simulated microgravity, while for the constant dark (DD) condition, the activity and sleep rhythms appeared disordered and the activity increased, thus decreasing the likelihood of waking up during the day. Light conditions, strains, and sexes, individually or in combination, had impacts on the simulated microgravity effects on behaviors. The clock genes and neurotransmitter-related genes had different degrees of response among sexes and strains, although the overall changes were slight. The results indicated that the normal photoperiod could ease the effects of simulated microgravity on fruit flies' activity and sleep and possible unidentified pathways involved in the regulatory mechanism need further exploration. This study is expected to provide ideas and references for studying the effects of microgravity on space life science."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41526-021-00157-5"xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/author | "Sun B."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/author | "Wang Y."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/author | "Tang C."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/author | "Zhang Z."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/author | "Zhang L."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/author | "Jiang Z."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/author | "Cai P."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/author | "Ding B."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/name | "NPJ Microgravity"xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/pages | "27"xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/title | "Alterations in the activity and sleep of Drosophila melanogaster under simulated microgravity."xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/34294729 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34294729 |
| http://purl.uniprot.org/citations/34294729 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34294729 |
| http://purl.uniprot.org/uniprot/#_A0A1W5PW00-mappedCitation-34294729 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34294729 |
| http://purl.uniprot.org/uniprot/#_A0A9F2GM11-mappedCitation-34294729 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34294729 |
| http://purl.uniprot.org/uniprot/#_B5X0J4-mappedCitation-34294729 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34294729 |
| http://purl.uniprot.org/uniprot/#_P49021-mappedCitation-34294729 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34294729 |
| http://purl.uniprot.org/uniprot/#_M9PGJ3-mappedCitation-34294729 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34294729 |
| http://purl.uniprot.org/uniprot/#_P07663-mappedCitation-34294729 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34294729 |