| http://purl.uniprot.org/citations/34389707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34389707 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34389707 | http://www.w3.org/2000/01/rdf-schema#comment | "In bacteria, trans-translation is the main rescue system, freeing ribosomes stalled on defective messenger RNAs. This mechanism is driven by small protein B (SmpB) and transfer-messenger RNA (tmRNA), a hybrid RNA known to have both a tRNA-like and an mRNA-like domain. Here we present four cryo-EM structures of the ribosome during trans-translation at resolutions from 3.0 to 3.4 Å. These include the high-resolution structure of the whole pre-accommodated state, as well as structures of the accommodated state, the translocated state, and a translocation intermediate. Together, they shed light on the movements of the tmRNA-SmpB complex in the ribosome, from its delivery by the elongation factor EF-Tu to its passage through the ribosomal A and P sites after the opening of the B1 bridges. Additionally, we describe the interactions between the tmRNA-SmpB complex and the ribosome. These explain why the process does not interfere with canonical translation."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-021-24881-4"xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-021-24881-4"xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/author | "Gillet R."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/author | "Gillet R."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/author | "D'Urso G."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/author | "D'Urso G."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/author | "Giudice E."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/author | "Giudice E."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/author | "Chat S."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/author | "Chat S."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/author | "Guyomar C."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/author | "Guyomar C."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/name | "Nat. Commun."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/pages | "4909"xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/pages | "4909"xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/title | "Structures of tmRNA and SmpB as they transit through the ribosome."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/title | "Structures of tmRNA and SmpB as they transit through the ribosome."xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/34389707 | http://purl.uniprot.org/core/volume | "12"xsd:string |