| http://purl.uniprot.org/citations/34391065 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34391065 | http://www.w3.org/2000/01/rdf-schema#comment | "Alectinib, a highly selective inhibitor of anaplastic lymphoma kinase (ALK), has shown a high response rate and long progression-free survival in primary treatment of ALK-positive non-small-cell lung cancer (NSCLC). De novo resistance or refractory subtype is rare event. Herein, we identify the first case with serial next-generation sequencing (NGS) results that harboured a rare echinoderm microtubule associated protein like 4 gene (EML4) -ALK (breaking site at exon 19) fusion in a lung adenocarcinoma (LUAD) patient who acquired alectinib resistance rapidly (less than 3 months), followed by multi-drug resistance and short survival time."xsd:string |
| http://purl.uniprot.org/citations/34391065 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.lungcan.2021.07.020"xsd:string |
| http://purl.uniprot.org/citations/34391065 | http://purl.uniprot.org/core/author | "Fan M."xsd:string |
| http://purl.uniprot.org/citations/34391065 | http://purl.uniprot.org/core/author | "Liu D."xsd:string |
| http://purl.uniprot.org/citations/34391065 | http://purl.uniprot.org/core/author | "Zhang C."xsd:string |
| http://purl.uniprot.org/citations/34391065 | http://purl.uniprot.org/core/author | "Xu X."xsd:string |
| http://purl.uniprot.org/citations/34391065 | http://purl.uniprot.org/core/author | "Wen J."xsd:string |
| http://purl.uniprot.org/citations/34391065 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34391065 | http://purl.uniprot.org/core/name | "Lung Cancer"xsd:string |
| http://purl.uniprot.org/citations/34391065 | http://purl.uniprot.org/core/pages | "32-35"xsd:string |
| http://purl.uniprot.org/citations/34391065 | http://purl.uniprot.org/core/title | "Identification of a EML4-ALK exon 19 fusion variant in lung adenocarcinoma and alectinib resistance."xsd:string |
| http://purl.uniprot.org/citations/34391065 | http://purl.uniprot.org/core/volume | "160"xsd:string |
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