| http://purl.uniprot.org/citations/34405343 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34405343 | http://www.w3.org/2000/01/rdf-schema#comment | "Preimplantation embryo development is characterized by drastic nuclear reprogramming and dynamic stage-specific gene expression. Key regulators of this earliest developmental stage have not been revealed. In the present study, a "non-classical" nuclear-localization pattern of eIF1A was observed during early developmental stages of mouse preimplantation embryo before late-morula. In particular, eIF1A is most highly expressed in the nuclear of 2-cell embryo. Knockdown eIF1A by siRNA microinjection affected the development of mouse preimplantation embryo, resulted in decreased blastocyst formation rate. CDX2 protein expression level significantly down-regulated after eIF1A knockdown in morula stage. In addition, the mRNA expression level of Hsp70.1 was also decreased in 2-cell embryo. The results indicate an indispensable role of eIF1A in mouse preimplantation embryos."xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10735-021-10014-0"xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/author | "Lin J."xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/author | "Sun J."xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/author | "Su Y."xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/author | "Wang S."xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/author | "Xu S."xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/author | "Lv C."xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/author | "Mo K."xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/name | "J Mol Histol"xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/pages | "965-973"xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/title | "Nuclear-localized eukaryotic translation initiation factor 1A is involved in mouse preimplantation embryo development."xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://purl.uniprot.org/core/volume | "52"xsd:string |
| http://purl.uniprot.org/citations/34405343 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34405343 |
| http://purl.uniprot.org/citations/34405343 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34405343 |
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| http://purl.uniprot.org/uniprot/#_A0A2I6EDJ6-mappedCitation-34405343 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34405343 |
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| http://purl.uniprot.org/uniprot/#_A0A494BB48-mappedCitation-34405343 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34405343 |
| http://purl.uniprot.org/uniprot/#_A0A494BB95-mappedCitation-34405343 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34405343 |
| http://purl.uniprot.org/uniprot/#_A7KBS4-mappedCitation-34405343 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34405343 |