http://purl.uniprot.org/citations/34437840 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/34437840 | http://www.w3.org/2000/01/rdf-schema#comment | "Upon viral infection, natural killer (NK) cells expressing certain germline-encoded receptors are selected, expanded, and maintained in an adaptive-like manner. Currently, these are thought to differentiate along a common pathway. However, by fate mapping of single NK cells upon murine cytomegalovirus (MCMV) infection, we identified two distinct NK cell lineages that contributed to adaptive-like responses. One was equivalent to conventional NK (cNK) cells while the other was transcriptionally similar to type 1 innate lymphoid cells (ILC1s). ILC1-like NK cells showed splenic residency and strong cytokine production but also recognized and killed MCMV-infected cells, guided by activating receptor Ly49H. Moreover, they induced clustering of conventional type 1 dendritic cells and facilitated antigen-specific T cell priming early during MCMV infection, which depended on Ly49H and the NK cell-intrinsic expression of transcription factor Batf3. Thereby, ILC1-like NK cells bridge innate and adaptive viral recognition and unite critical features of cNK cells and ILC1s."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.immuni.2021.08.002"xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Zhang Q."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Sun J.C."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Busch D.H."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Victora G.D."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Cicin-Sain L."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Hofer T."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Schiemann M."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Hensel I."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Meiser P."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Gasteiger G."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Grassmann S."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Buchholz V.R."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Flossdorf M."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Bottcher J.P."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Ersching J."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Leube J."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Jarosch S."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Chaudhry M.Z."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Andrae I."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Flommersfeld S."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/author | "Pachmayr L.O."xsd:string |
http://purl.uniprot.org/citations/34437840 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |