| http://purl.uniprot.org/citations/34458755 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34458755 | http://www.w3.org/2000/01/rdf-schema#comment | "Cellulases and related β-1,4-glucanases are essential components of lignocellulose-degrading enzyme mixtures. The detection of β-1,4-glucanase activity typically relies on monitoring the breakdown of purified lignocellulose-derived substrates or synthetic chromogenic substrates, limiting the activities which can be detected and complicating the tracing of activity back to specific components within complex enzyme mixtures. As a tool for the rapid detection and identification of β-1,4-glucanases, a series of glycosylated cyclophellitol inhibitors mimicking β-1,4-glucan oligosaccharides have been synthesised. These compounds are highly efficient inhibitors of HiCel7B, a well-known GH7 endo-β-1,4-glucanase. An elaborated activity-based probe facilitated the direct detection and identification of β-1,4-glucanases within a complex fungal secretome without any detectable cross-reactivity with β-d-glucosidases. These probes and inhibitors add valuable new capacity to the growing toolbox of cyclophellitol-derived probes for the activity-based profiling of biomass-degrading enzymes."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.org/dc/terms/identifier | "doi:10.1039/d0cb00045k"xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "Davies G.J."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "Jiang J."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "van Wezel G.P."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "van der Marel G.A."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "Overkleeft H.S."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "Ram A.F.J."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "Codee J.D.C."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "de Boer C."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "Florea B.I."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "Schroder S.P."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "McGregor N.G.S."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "Reijngoud J."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/author | "Peterse E."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/name | "RSC Chem Biol"xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/pages | "148-155"xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/title | "Glycosylated cyclophellitol-derived activity-based probes and inhibitors for cellulases."xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://purl.uniprot.org/core/volume | "1"xsd:string |
| http://purl.uniprot.org/citations/34458755 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34458755 |
| http://purl.uniprot.org/citations/34458755 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34458755 |
| http://purl.uniprot.org/uniprot/#_P56680-mappedCitation-34458755 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34458755 |
| http://purl.uniprot.org/uniprot/P56680 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/34458755 |