| http://purl.uniprot.org/citations/34555253 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34555253 | http://www.w3.org/2000/01/rdf-schema#comment | "This study was conducted to describe the association between the genetic variation of the recently identified immune checkpoint molecules B7-H3 and B7-H4, and the susceptibility to ankylosing spondylitis (AS). Two single nucleotide polymorphisms (SNPs) of B7-H3 gene and three SNPs of B7-H4 gene were genotyped in 649 AS patients and 646 age- and sex-matched healthy controls. Allele, genotype frequencies and different inheritance models were performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs), and the demographic and clinical parameters of patients were recorded. Our data indicated that B7-H4 rs10801935 and rs3738414 polymorphisms were correlated with AS susceptibility. In the stratification analyses, the minor A allele and GA genotype of B7-H4 rs3738414 increased the risk of AS in male patients (OR = 1.244, 95%CI = 1.026-1.508; OR = 1.453, 95%CI = 1.120-1.886, respectively). However, the association did not reach statistical significance after Bonferroni correction. Furthermore, haplotype analysis revealed that B7-H4 haplotype block TAG was a risk factor for the onset of AS (OR = 1.190, 95%CI = 1.020-1.389). These findings suggested that B7-H4 gene polymorphism may contribute to AS susceptibility in eastern Chinese Han population."xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.org/dc/terms/identifier | "doi:10.1111/iji.12559"xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/author | "Chen Y."xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/author | "Shen J."xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/author | "Xu W."xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/author | "Yang H."xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/author | "Xu S."xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/author | "Pan F."xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/author | "Shao M."xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/name | "Int J Immunogenet"xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/pages | "500-509"xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/title | "Association analysis of B7-H3 and B7-H4 gene single nucleotide polymorphisms in susceptibility to ankylosing spondylitis in eastern Chinese Han population."xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://purl.uniprot.org/core/volume | "48"xsd:string |
| http://purl.uniprot.org/citations/34555253 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34555253 |
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| http://purl.uniprot.org/uniprot/#_Q9UM44-mappedCitation-34555253 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34555253 |