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http://purl.uniprot.org/citations/34557481http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/34557481http://www.w3.org/2000/01/rdf-schema#comment"In multicellular organisms, tissue generation, maintenance, and homeostasis depend on stem cells. Cellular metabolic status is an essential component of different differentiated states, from stem to fully differentiated cells. Threonine (Thr) metabolism has emerged as a critical factor required to maintain pluripotent/multipotent stem cells in both plants and animals. Thus, both kingdoms conserved or converged upon this fundamental feature of stem cell function. Here, we examine similarities and differences in Thr metabolism-dependent mechanisms supporting stem cell maintenance in these two kingdoms. We then consider common features of Thr metabolism in stem cell maintenance and predict and speculate that some knowledge about Thr metabolism and its role in stem cell function in one kingdom may apply to the other. Finally, we outline future research directions to explore these hypotheses."xsd:string
http://purl.uniprot.org/citations/34557481http://purl.org/dc/terms/identifier"doi:10.3389/fcell.2021.672545"xsd:string
http://purl.uniprot.org/citations/34557481http://purl.uniprot.org/core/author"Dubrovsky J.G."xsd:string
http://purl.uniprot.org/citations/34557481http://purl.uniprot.org/core/author"Diaz de la Garza R.I."xsd:string
http://purl.uniprot.org/citations/34557481http://purl.uniprot.org/core/author"Van Winkle L.J."xsd:string
http://purl.uniprot.org/citations/34557481http://purl.uniprot.org/core/author"Sahoo D.P."xsd:string
http://purl.uniprot.org/citations/34557481http://purl.uniprot.org/core/date"2021"xsd:gYear
http://purl.uniprot.org/citations/34557481http://purl.uniprot.org/core/name"Front Cell Dev Biol"xsd:string
http://purl.uniprot.org/citations/34557481http://purl.uniprot.org/core/pages"672545"xsd:string
http://purl.uniprot.org/citations/34557481http://purl.uniprot.org/core/title"Interkingdom Comparison of Threonine Metabolism for Stem Cell Maintenance in Plants and Animals."xsd:string
http://purl.uniprot.org/citations/34557481http://purl.uniprot.org/core/volume"9"xsd:string
http://purl.uniprot.org/citations/34557481http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/34557481
http://purl.uniprot.org/citations/34557481http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/34557481
http://purl.uniprot.org/uniprot/#_Q9S7B5-mappedCitation-34557481http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/34557481
http://purl.uniprot.org/uniprot/Q9S7B5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/34557481