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http://purl.uniprot.org/citations/34584739http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/34584739http://www.w3.org/2000/01/rdf-schema#comment"Time-resolved crystallography of biomolecules in action has advanced rapidly as methods for serial crystallography have improved, but the large number of crystals and the complex experimental infrastructure that are required remain serious obstacles to its widespread application. Here, millisecond mix-and-quench crystallography (MMQX) has been developed, which yields millisecond time-resolved data using far fewer crystals and routine remote synchrotron data collection. To demonstrate the capabilities of MMQX, the conversion of oxaloacetic acid to phosphoenolpyruvate by phosphoenolpyruvate carboxy-kinase (PEPCK) is observed with a time resolution of 40 ms. By lowering the entry barrier to time-resolved crystallography, MMQX should enable a broad expansion in structural studies of protein dynamics."xsd:string
http://purl.uniprot.org/citations/34584739http://purl.org/dc/terms/identifier"doi:10.1107/s2052252521007053"xsd:string
http://purl.uniprot.org/citations/34584739http://purl.uniprot.org/core/author"Holyoak T."xsd:string
http://purl.uniprot.org/citations/34584739http://purl.uniprot.org/core/author"Clinger J.A."xsd:string
http://purl.uniprot.org/citations/34584739http://purl.uniprot.org/core/author"McLeod M.J."xsd:string
http://purl.uniprot.org/citations/34584739http://purl.uniprot.org/core/author"Thorne R.E."xsd:string
http://purl.uniprot.org/citations/34584739http://purl.uniprot.org/core/author"Moreau D.W."xsd:string
http://purl.uniprot.org/citations/34584739http://purl.uniprot.org/core/date"2021"xsd:gYear
http://purl.uniprot.org/citations/34584739http://purl.uniprot.org/core/name"IUCrJ"xsd:string
http://purl.uniprot.org/citations/34584739http://purl.uniprot.org/core/pages"784-792"xsd:string
http://purl.uniprot.org/citations/34584739http://purl.uniprot.org/core/title"Millisecond mix-and-quench crystallography (MMQX) enables time-resolved studies of PEPCK with remote data collection."xsd:string
http://purl.uniprot.org/citations/34584739http://purl.uniprot.org/core/volume"8"xsd:string
http://purl.uniprot.org/citations/34584739http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/34584739
http://purl.uniprot.org/citations/34584739http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/34584739
http://purl.uniprot.org/uniprot/#_P07379-mappedCitation-34584739http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/34584739
http://purl.uniprot.org/uniprot/P07379http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/34584739