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http://purl.uniprot.org/citations/34688245http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/34688245http://www.w3.org/2000/01/rdf-schema#comment"

Background/aim

Human HIV-1 TAT interactive protein 2 (HTATIP2/TIP30) is a gene that is extensively expressed in human tissues as well as in tumor tissues. This study aimed to explore the potential role of HTATIP2/TIP30 in contact dermatitis (CD), which is one of the most common inflammatory cutaneous conditions.

Materials and methods

This cross-sectional study involved adult patients with acute contact dermatitis who were admitted to the outpatient dermatology clinic of a tertiary hospital and healthy adult volunteers without any cutaneous or systemic diseases. The blood concentration of HTATIP2/TIP30 was measured using ELISA kits.

Results

The research sample consisted of 31 patients with CD (18 males, 13 females) and 20 healthy control subjects (14 males, 6 females). The mean ages of the patients with CD and healthy volunteers were 37 and 30 years, respectively (p > 0.05). The mean value of serum HTATIP2/TIP30 levels in patients with CD was 1.65 ng ml–1, which is 0.60 ng ml–1 in the control group (p = 0.02)

Conclusion

In this study, serum levels of HTATIP2/TIP30 were statistically significantly higher in patients with CD when compared to healthy controls. This outcome may indicate possible role of HTATIP2/TIP30 in the pathogenesis of CD."xsd:string
http://purl.uniprot.org/citations/34688245http://purl.org/dc/terms/identifier"doi:10.3906/sag-2106-81"xsd:string
http://purl.uniprot.org/citations/34688245http://purl.uniprot.org/core/author"Akdeniz N."xsd:string
http://purl.uniprot.org/citations/34688245http://purl.uniprot.org/core/author"Bilen H."xsd:string
http://purl.uniprot.org/citations/34688245http://purl.uniprot.org/core/author"Elmas O.F."xsd:string
http://purl.uniprot.org/citations/34688245http://purl.uniprot.org/core/author"Metin M.S."xsd:string
http://purl.uniprot.org/citations/34688245http://purl.uniprot.org/core/date"2021"xsd:gYear
http://purl.uniprot.org/citations/34688245http://purl.uniprot.org/core/name"Turk J Med Sci"xsd:string
http://purl.uniprot.org/citations/34688245http://purl.uniprot.org/core/pages"3017-3021"xsd:string
http://purl.uniprot.org/citations/34688245http://purl.uniprot.org/core/title"The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis."xsd:string
http://purl.uniprot.org/citations/34688245http://purl.uniprot.org/core/volume"51"xsd:string
http://purl.uniprot.org/citations/34688245http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/34688245
http://purl.uniprot.org/citations/34688245http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/34688245
http://purl.uniprot.org/uniprot/#_Q9BUP3-mappedCitation-34688245http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/34688245
http://purl.uniprot.org/uniprot/Q9BUP3http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/34688245