| http://purl.uniprot.org/citations/34723832 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34723832 | http://www.w3.org/2000/01/rdf-schema#comment | "miR-23a-3p and miR-23b-3p are members of the miR-23~27~24-2 superfamily. The role of miR-23a/b-3p in regulating hepatic lipid accumulation is still unknown. Here, we found that increased miR-23a-3p and miR-23b-3p levels were accompanied by an increase in the protein levels of the sterol regulatory element-binding protein-1 (SREBP-1) and fatty acid synthase (FAS) in the steatotic livers of mice fed a high-fat diet and leptin receptor-deficient type 2 diabetic mice (db/db). Importantly, overexpression of miR-23a/b-3p in Hep1-6 cells elevated the intracellular triglyceride level and upregulated the expression of Srebp-1c and Fas. Taken together, these results suggested that miR-23a/b-3p enhanced mRNA stability by binding the 5'-UTR of Srebp-1c and Fas mRNA, thereby promoting triglyceride accumulation in hepatocytes."xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.org/dc/terms/identifier | "doi:10.1530/jme-20-0324"xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/author | "Huang X."xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/author | "Li L."xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/author | "Zhang X."xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/author | "Tang W."xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/author | "Ren H."xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/author | "Shen T."xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/author | "Dou L."xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/name | "J Mol Endocrinol"xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/pages | "35-49"xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/title | "miR-23a/b-3p promotes hepatic lipid accumulation by regulating Srebp-1c and Fas."xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://purl.uniprot.org/core/volume | "68"xsd:string |
| http://purl.uniprot.org/citations/34723832 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34723832 |
| http://purl.uniprot.org/citations/34723832 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34723832 |
| http://purl.uniprot.org/uniprot/#_Q3UHT6-mappedCitation-34723832 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34723832 |
| http://purl.uniprot.org/uniprot/#_Q3V274-mappedCitation-34723832 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34723832 |
| http://purl.uniprot.org/uniprot/#_Q3UMP4-mappedCitation-34723832 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34723832 |
| http://purl.uniprot.org/uniprot/#_P19096-mappedCitation-34723832 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34723832 |
| http://purl.uniprot.org/uniprot/#_O89060-mappedCitation-34723832 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34723832 |
| http://purl.uniprot.org/uniprot/#_Q3UEI6-mappedCitation-34723832 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34723832 |
| http://purl.uniprot.org/uniprot/#_Q3TB22-mappedCitation-34723832 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34723832 |