| http://purl.uniprot.org/citations/34737342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34737342 | http://www.w3.org/2000/01/rdf-schema#comment | "The anterior pituitary gland regulates growth, metabolism, and reproduction by secreting hormones. Folliculo-stellate (FS) cells are non-endocrine cells located among hormone-producing cells in the anterior pituitary glands. They form follicular lumens, which are sealed by tight junctions (TJs). Although FS cells are hypothesized to contribute to fine-tuning of endocrine cells, little is known about the exact roles of FS cells. Here, we investigated the molecular composition of TJs in FS cells. We demonstrated that occludin is a good marker for TJs in the pituitary gland and examined the structure of the lumens surrounded by FS cells. We also found that claudin-9 is a major component of TJs in the FS cells. In immunoelectron microscopy, claudin-9 was specifically localized at TJs of the FS cells. The expression of claudin-9 was gradually increased in the pituitary gland after birth, suggesting that claudin-9 is developmentally regulated and performs some specific functions on the paracellular barrier of follicles in the pituitary gland. Furthermore, we found that angulin-1, angulin-2, and tricellulin are localized at the tricellular contacts of the FS cells. Our findings provide a first comprehensive molecular profile of TJs in the FS cells, and may lead us towards unveiling the FS cell functions."xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41598-021-01004-z"xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/author | "Chiba H."xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/author | "Ozeki K."xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/author | "Higashi T."xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/author | "Furuse M."xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/author | "Furuse K."xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/author | "Higashi A.Y."xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/name | "Sci Rep"xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/pages | "21642"xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/title | "Claudin-9 constitutes tight junctions of folliculo-stellate cells in the anterior pituitary gland."xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://purl.uniprot.org/core/volume | "11"xsd:string |
| http://purl.uniprot.org/citations/34737342 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34737342 |
| http://purl.uniprot.org/citations/34737342 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34737342 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YVY9-mappedCitation-34737342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34737342 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YWD2-mappedCitation-34737342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34737342 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YXF0-mappedCitation-34737342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34737342 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YXV2-mappedCitation-34737342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34737342 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YY19-mappedCitation-34737342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34737342 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YY76-mappedCitation-34737342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34737342 |
| http://purl.uniprot.org/uniprot/#_A0A0M6L0K7-mappedCitation-34737342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34737342 |
| http://purl.uniprot.org/uniprot/#_A0A0U1RPB2-mappedCitation-34737342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34737342 |
| http://purl.uniprot.org/uniprot/#_A0A1B0GQV1-mappedCitation-34737342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34737342 |