| http://purl.uniprot.org/citations/34762476 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34762476 | http://www.w3.org/2000/01/rdf-schema#comment | "In mammals and flies, only one cell in a multicellular female germline cyst becomes an oocyte, but how symmetry is broken to select the oocyte is unknown. Here, we show that the microtubule (MT) minus end-stabilizing protein Patronin/CAMSAP marks the future Drosophila oocyte and is required for oocyte specification. The spectraplakin Shot recruits Patronin to the fusome, a branched structure extending into all cyst cells. Patronin stabilizes more MTs in the cell with the most fusome material. Our data suggest that this weak asymmetry is amplified by Dynein-dependent transport of Patronin-stabilized MTs. This forms a polarized MT network, along which Dynein transports oocyte determinants into the presumptive oocyte. Thus, Patronin amplifies a weak fusome anisotropy to break symmetry and select one cell to become the oocyte."xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.abj3125"xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://purl.uniprot.org/core/author | "St Johnston D."xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://purl.uniprot.org/core/author | "Jakobs M."xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://purl.uniprot.org/core/author | "Nashchekin D."xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://purl.uniprot.org/core/author | "Busby L."xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://purl.uniprot.org/core/author | "Squires I."xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/34762476 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://purl.uniprot.org/core/pages | "874-879"xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://purl.uniprot.org/core/title | "Symmetry breaking in the female germline cyst."xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://purl.uniprot.org/core/volume | "374"xsd:string |
| http://purl.uniprot.org/citations/34762476 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34762476 |
| http://purl.uniprot.org/citations/34762476 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34762476 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFU3-mappedCitation-34762476 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34762476 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KET5-mappedCitation-34762476 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34762476 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KEY4-mappedCitation-34762476 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34762476 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KEY6-mappedCitation-34762476 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34762476 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFA4-mappedCitation-34762476 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34762476 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K718-mappedCitation-34762476 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34762476 |
| http://purl.uniprot.org/uniprot/#_E1JH62-mappedCitation-34762476 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34762476 |
| http://purl.uniprot.org/uniprot/#_E1JH63-mappedCitation-34762476 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34762476 |
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| http://purl.uniprot.org/uniprot/#_E1JH65-mappedCitation-34762476 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34762476 |