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http://purl.uniprot.org/citations/3480538http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3480538http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3480538http://www.w3.org/2000/01/rdf-schema#comment"Among the earliest expressed antigens on the surface of activated human lymphocytes is the surface antigen 4F2. We have used DNA-mediated gene transfer and fluorescence-activated cell sorting to obtain cell lines that contain the gene encoding the large subunit of the human 4F2 antigen in a mouse L-cell background. Human DNAs cloned from these cell lines were subsequently used as hybridization probes to isolate a full-length cDNA clone expressing 4F2. Sequence analysis of the coding region has revealed an amino acid sequence of 529 residues. Hydrophobicity plotting has predicted a probable structure for the protein that includes an external carboxyl terminus, an internal leader sequence, a single hydrophobic transmembrane domain, and two possible membrane-associated domains. The 4F2 cDNA detects a single 1.8-kilobase mRNA in T-cell and B-cell lines. RNA gel blot analysis of RNA derived from quiescent and serum-stimulated Swiss 3T3 fibroblasts reveals a cell-cycle modulation of 4F2 gene expression: the mRNA is present in quiescent fibroblasts but increases 8-fold 24-36 hr after stimulation, at the time of maximal DNA synthesis."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.org/dc/terms/identifier"doi:10.1073/pnas.84.24.9204"xsd:string
http://purl.uniprot.org/citations/3480538http://purl.org/dc/terms/identifier"doi:10.1073/pnas.84.24.9204"xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/author"Glick A.B."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/author"Glick A.B."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/author"Lumadue J.A."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/author"Lumadue J.A."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/author"Ruddle F.H."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/author"Ruddle F.H."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/date"1987"xsd:gYear
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/date"1987"xsd:gYear
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/pages"9204-9208"xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/pages"9204-9208"xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/title"Cloning, sequence analysis, and expression of the large subunit of the human lymphocyte activation antigen 4F2."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/title"Cloning, sequence analysis, and expression of the large subunit of the human lymphocyte activation antigen 4F2."xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/volume"84"xsd:string
http://purl.uniprot.org/citations/3480538http://purl.uniprot.org/core/volume"84"xsd:string
http://purl.uniprot.org/citations/3480538http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3480538
http://purl.uniprot.org/citations/3480538http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3480538
http://purl.uniprot.org/citations/3480538http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/3480538
http://purl.uniprot.org/citations/3480538http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/3480538