http://purl.uniprot.org/citations/34833441 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/34833441 | http://www.w3.org/2000/01/rdf-schema#comment | "Background and Objectives: Telomeric zinc finger-associated protein (TZAP) is a telomere regulation protein, previously known as ZBTB48. It binds preferentially to elongated telomeres, competing with telomeric repeat factors 1 and 2. TZAP expression may be associated with carcinogenesis, however; this study has not yet been performed in lung cancer. In this study, we examined the clinicopathological and prognostic values of TZAP expression in non-small cell lung cancer (NSCLC). Materials and Methods: Data were collected from The Cancer Genome Atlas. The clinical and prognostic values of TZAP for NSCLC were examined in adenocarcinoma (AD) and squamous cell carcinoma (SCC). Results: TZAP expression significantly increased in NSCLC tissues compared with normal tissues. In AD, TZAP expression was lower in patients with higher T stage (p = 0.005), and was associated with lymph node stage in SCC (p = 0.005). Survival analysis showed shorter disease-free survival in AD patients with lower TZAP expression (p = 0.047). TZAP expression did not have other clinical or prognostic value for AD and SCC. Conclusions: TZAP expression is a potential prognostic marker for NSCLC, especially in patients with AD."xsd:string |
http://purl.uniprot.org/citations/34833441 | http://purl.org/dc/terms/identifier | "doi:10.3390/medicina57111223"xsd:string |
http://purl.uniprot.org/citations/34833441 | http://purl.uniprot.org/core/author | "Lee J.H."xsd:string |
http://purl.uniprot.org/citations/34833441 | http://purl.uniprot.org/core/author | "Lee D.H."xsd:string |
http://purl.uniprot.org/citations/34833441 | http://purl.uniprot.org/core/author | "Kim G.J."xsd:string |
http://purl.uniprot.org/citations/34833441 | http://purl.uniprot.org/core/author | "Chae M."xsd:string |
http://purl.uniprot.org/citations/34833441 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
http://purl.uniprot.org/citations/34833441 | http://purl.uniprot.org/core/name | "Medicina (Kaunas)"xsd:string |
http://purl.uniprot.org/citations/34833441 | http://purl.uniprot.org/core/pages | "1223"xsd:string |
http://purl.uniprot.org/citations/34833441 | http://purl.uniprot.org/core/title | "Prognostic Value of Telomeric Zinc Finger-Associated Protein Expression in Adenocarcinoma and Squamous Cell Carcinoma of Lung."xsd:string |
http://purl.uniprot.org/citations/34833441 | http://purl.uniprot.org/core/volume | "57"xsd:string |
http://purl.uniprot.org/citations/34833441 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34833441 |
http://purl.uniprot.org/citations/34833441 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34833441 |
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http://purl.uniprot.org/uniprot/#_B2R702-mappedCitation-34833441 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34833441 |
http://purl.uniprot.org/uniprot/#_P10074-mappedCitation-34833441 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34833441 |
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http://purl.uniprot.org/uniprot/P10074 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/34833441 |
http://purl.uniprot.org/uniprot/A8K291 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/34833441 |
http://purl.uniprot.org/uniprot/B2R702 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/34833441 |