| http://purl.uniprot.org/citations/34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/34849871 | http://www.w3.org/2000/01/rdf-schema#comment | "Many traits responsible for male reproduction evolve quickly, including gene expression phenotypes in germline and somatic male reproductive tissues. Rapid male evolution in polyandrous species is thought to be driven by competition among males for fertilizations and conflicts between male and female fitness interests that manifest in postcopulatory phenotypes. In Drosophila, seminal fluid proteins secreted by three major cell types of the male accessory gland and ejaculatory duct are required for female sperm storage and use, and influence female postcopulatory traits. Recent work has shown that these cell types have overlapping but distinct effects on female postcopulatory biology, yet relatively little is known about their evolutionary properties. Here, we use single-nucleus RNA-Seq of the accessory gland and ejaculatory duct from Drosophila melanogaster and two closely related species to comprehensively describe the cell diversity of these tissues and their transcriptome evolution for the first time. We find that seminal fluid transcripts are strongly partitioned across the major cell types, and expression of many other genes additionally defines each cell type. We also report previously undocumented diversity in main cells. Transcriptome divergence was found to be heterogeneous across cell types and lineages, revealing a complex evolutionary process. Furthermore, protein adaptation varied across cell types, with potential consequences for our understanding of selection on male postcopulatory traits."xsd:string |
| http://purl.uniprot.org/citations/34849871 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/iyab213"xsd:string |
| http://purl.uniprot.org/citations/34849871 | http://purl.uniprot.org/core/author | "Begun D.J."xsd:string |
| http://purl.uniprot.org/citations/34849871 | http://purl.uniprot.org/core/author | "Cridland J.M."xsd:string |
| http://purl.uniprot.org/citations/34849871 | http://purl.uniprot.org/core/author | "Majane A.C."xsd:string |
| http://purl.uniprot.org/citations/34849871 | http://purl.uniprot.org/core/date | "2022"xsd:gYear |
| http://purl.uniprot.org/citations/34849871 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/34849871 | http://purl.uniprot.org/core/pages | "iyab213"xsd:string |
| http://purl.uniprot.org/citations/34849871 | http://purl.uniprot.org/core/title | "Single-nucleus transcriptomes reveal evolutionary and functional properties of cell types in the Drosophila accessory gland."xsd:string |
| http://purl.uniprot.org/citations/34849871 | http://purl.uniprot.org/core/volume | "220"xsd:string |
| http://purl.uniprot.org/citations/34849871 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/34849871 |
| http://purl.uniprot.org/citations/34849871 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/34849871 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFI2-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFY1-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KET3-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KEZ8-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KF98-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFA2-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LFL2-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_A0A0S0WNN1-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_D5SHT8-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_P54352-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K7U4-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K801-mappedCitation-34849871 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/34849871 |