| http://purl.uniprot.org/citations/35101895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/35101895 | http://www.w3.org/2000/01/rdf-schema#comment | "Metabolomics analyses suggest changes in amino acid abundance, particularly l-arginine (L-ARG), occur in patients with tuberculosis. Immune cells require L-ARG to fuel effector functions following infection. We have previously described an L-ARG synthesis pathway in immune cells; however, its role in APCs has yet to be uncovered. Using a coculture system with mycobacterial-specific CD4+ T cells, we show APC L-ARG synthesis supported T cell viability and proliferation, and activated T cells contained APC-derived L-ARG. We hypothesize that APCs supply L-ARG to support T cell activation under nutrient-limiting conditions. This work expands the current model of APC-T cell interactions and provides insight into the effects of nutrient availability in immune cells."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.2100652"xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "Zhao J."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "Setchell K.D.R."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "Qualls J.E."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "Greis K.D."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "Schmidt S.M."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "Lange S.M."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "McKell M.C."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "Haffey W.D."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "Robillard M.C."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "Crowther R.R."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/author | "Wyder M.A."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/date | "2022"xsd:gYear |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/pages | "793-798"xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/title | "Cutting Edge: l-Arginine Transfer from Antigen-Presenting Cells Sustains CD4+ T Cell Viability and Proliferation."xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://purl.uniprot.org/core/volume | "208"xsd:string |
| http://purl.uniprot.org/citations/35101895 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/35101895 |
| http://purl.uniprot.org/citations/35101895 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/35101895 |
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| http://purl.uniprot.org/uniprot/#_F7D439-mappedCitation-35101895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/35101895 |
| http://purl.uniprot.org/uniprot/#_Q3UUH0-mappedCitation-35101895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/35101895 |