| http://purl.uniprot.org/citations/35139305 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/35139305 | http://www.w3.org/2000/01/rdf-schema#comment | "Vicilin-buried peptides (VBPs) from edible plants are derived from the N-terminal leader sequences (LSs) of seed storage proteins. VBPs are defined by a common α-hairpin fold mediated by conserved CxxxCx(10-14)CxxxC motifs. Here, peanut and walnut VBPs were characterized as potential mediators of both peanut/walnut allergenicity and cross-reactivity despite their low (∼17%) sequence identity. The structures of one peanut (AH1.1) and 3 walnut (JR2.1, JR2.2, JR2.3) VBPs were solved using solution NMR, revealing similar α-hairpin structures stabilized by disulfide bonds with high levels of surface similarity. Peptide microarrays identified several peptide sequences primarily on AH1.1 and JR2.1, which were recognized by peanut-, walnut-, and dual-allergic patient IgE, establishing these peanut and walnut VBPs as potential mediators of allergenicity and cross-reactivity. JR2.2 and JR2.3 displayed extreme resilience against endosomal digestion, potentially hindering epitope generation and likely contributing to their reduced allergic potential."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.org/dc/terms/identifier | "doi:10.1021/acs.jafc.1c07225"xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "Cheng H."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "Teuber S.S."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "Hurlburt B.K."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "Maleki S.J."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "Mueller G.A."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "DeRose E.F."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "Schein C.H."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "Foo A.C.Y."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "Gipson S.A.Y."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "Nesbit J.B."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/author | "Bushel P."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/date | "2022"xsd:gYear |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/name | "J Agric Food Chem"xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/pages | "2389-2400"xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/title | "Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides."xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://purl.uniprot.org/core/volume | "70"xsd:string |
| http://purl.uniprot.org/citations/35139305 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/35139305 |
| http://purl.uniprot.org/citations/35139305 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/35139305 |
| http://purl.uniprot.org/uniprot/#_P43238-mappedCitation-35139305 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/35139305 |
| http://purl.uniprot.org/uniprot/#_Q9SEW4-mappedCitation-35139305 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/35139305 |
| http://purl.uniprot.org/uniprot/Q9SEW4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/35139305 |
| http://purl.uniprot.org/uniprot/P43238 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/35139305 |