http://purl.uniprot.org/citations/35283446 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/35283446 | http://www.w3.org/2000/01/rdf-schema#comment | "Saccharomyces cerevisiae -like 1 ( SEC14L1 ) is a member of the SEC14 family and is involved in liposoluble vitamin transfer, and in a large cohort of breast cancer cases, was one of the genes most significantly associated with lymphovascular invasion (LVI), and had a significant relationship with human epidermal growth factor receptor 2 status, survival, and histologic grade. In this study, 111 separate gynecologic tumors were studied for SEC14L1 protein expression, including: uterine adenosarcoma, ovarian clear cell carcinoma, endometrial stromal sarcoma, endometrioid carcinoma of the uterus, high-grade serous carcinoma, ovarian endometrioid carcinoma, uterine leiomyosarcoma, low-grade serous carcinoma, uterine carcinosarcoma, and uterine serous carcinoma (USC). Overall, LVI was noted in 31/111 (28%) cases, highest in uterine carcinosarcoma (5/11; 45%), high-grade serous carcinoma (9/21; 43%), and ovarian clear cell carcinoma (4/10; 40%). SEC14L1 was positive in 25/111 (23%) cases; the highest percentage and only statistically significant finding by tumor type was USC at 9/12 (75%) cases positive. No relation between LVI or survival and SEC14L1 expression was noted. The relation between USC, a tumor known to show human epidermal growth factor receptor 2 overexpression and SEC14L1 is a novel finding, the significance of which warrants further study."xsd:string |
http://purl.uniprot.org/citations/35283446 | http://purl.org/dc/terms/identifier | "doi:10.1097/pgp.0000000000000866"xsd:string |
http://purl.uniprot.org/citations/35283446 | http://purl.uniprot.org/core/author | "Quddus M.R."xsd:string |
http://purl.uniprot.org/citations/35283446 | http://purl.uniprot.org/core/author | "Banet N."xsd:string |
http://purl.uniprot.org/citations/35283446 | http://purl.uniprot.org/core/author | "Masnick M."xsd:string |
http://purl.uniprot.org/citations/35283446 | http://purl.uniprot.org/core/date | "2023"xsd:gYear |
http://purl.uniprot.org/citations/35283446 | http://purl.uniprot.org/core/name | "Int J Gynecol Pathol"xsd:string |
http://purl.uniprot.org/citations/35283446 | http://purl.uniprot.org/core/pages | "136-142"xsd:string |
http://purl.uniprot.org/citations/35283446 | http://purl.uniprot.org/core/title | "Evaluation of Saccharomyces cerevisiae -like 1 (SEC14L1) in Gynecologic Malignancies Shows Overexpression in Endometrial Serous Carcinoma."xsd:string |
http://purl.uniprot.org/citations/35283446 | http://purl.uniprot.org/core/volume | "42"xsd:string |
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