http://purl.uniprot.org/citations/3555842 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3555842 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3555842 | http://www.w3.org/2000/01/rdf-schema#comment | "Cytoplasmic granules of cytolytic T lymphocytes (CTLs) contain, in addition to the pore-forming protein perforin, a family of highly homologous serine esterases, granzymes A-H. The serine esterase affinity label diisopropyl fluorophosphate reacts strongly with granzymes A and D, to a lesser extent with B, E, F, G, and H, and not at all with C and F. For granzymes A and D, synthetic substrates have been found. Antibodies raised against granzyme B strongly cross-react with A, G, and H, and antibodies to granzyme D recognize C, E, and F. These antigenic relationships correlate with similarities in the N-terminal amino acid sequences. At least 60% homology is observed between the eight proteins, and all are similar to rat mast cell protease 2. Sequence analysis suggests the identity of granzyme A with a protease predicted from a CTL-specific cDNA clone (H factor) and of granzyme B, G, or H with a protein encoded by the CTL-specific cDNA clone CTLA 1/CCP 1."xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(87)90544-7"xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(87)90544-7"xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/author | "Tschopp J."xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/author | "Tschopp J."xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/author | "Masson D."xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/author | "Masson D."xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/pages | "679-685"xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/pages | "679-685"xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/title | "A family of serine esterases in lytic granules of cytolytic T lymphocytes."xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/title | "A family of serine esterases in lytic granules of cytolytic T lymphocytes."xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/volume | "49"xsd:string |
http://purl.uniprot.org/citations/3555842 | http://purl.uniprot.org/core/volume | "49"xsd:string |
http://purl.uniprot.org/citations/3555842 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3555842 |
http://purl.uniprot.org/citations/3555842 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3555842 |
http://purl.uniprot.org/citations/3555842 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3555842 |
http://purl.uniprot.org/citations/3555842 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3555842 |
http://purl.uniprot.org/uniprot/P11033 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/3555842 |
http://purl.uniprot.org/uniprot/P08884 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/3555842 |