| http://purl.uniprot.org/citations/35607764 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/35607764 | http://www.w3.org/2000/01/rdf-schema#comment | "Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), which suppresses T cell proliferation, is a promising candidate for the susceptibility genes to rheumatic arthritis diseases (RA). This study aims to examine the association between the polymorphisms of the CTLA-4 exon 1(+ 49) genes with RA in the Qazvin city of Iran population. The polymerase chain reaction of genomic DNA-restriction fragment length polymorphism (PCR-RFLP) was applied to genotype the CTLA-4 exon 1(+ 49) polymorphisms in 105 RA patients and 90 control subjects. Laboratory diagnostic tests were also measured for RA and control groups. Our results did not demonstrate a significant difference in allele and genotype frequencies of the CTLA-4 exon 1(+ 49) between RA patients and the control group (p < .0001). There was no significant difference in age at onset, CRP, RF value in patients with RA according to the CTLA-4 polymorphisms; just anti-CCP showed a significant difference. Our data declared that polymorphisms of CTLA-4 exon 1(+ 49) genes are not correlated with RA susceptibility and its clinical and paraclinical manifestations."xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.org/dc/terms/identifier | "doi:10.1080/15321819.2022.2076109"xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/author | "Khalaji M."xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/author | "Javadi A."xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/author | "Maali A."xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/author | "Foroughi F."xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/author | "Sahmani M."xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/author | "Keshavarz Shahbaz S."xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/author | "Lashgari M."xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/date | "2022"xsd:gYear |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/name | "J Immunoassay Immunochem"xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/pages | "480-492"xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/title | "Survey of the association between polymorphisms of CTLA-4 exon 1 49 A/G genes with rheumatoid arthritis in Iran."xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://purl.uniprot.org/core/volume | "43"xsd:string |
| http://purl.uniprot.org/citations/35607764 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/35607764 |
| http://purl.uniprot.org/citations/35607764 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/35607764 |
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