| http://purl.uniprot.org/citations/35641515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/35641515 | http://www.w3.org/2000/01/rdf-schema#comment | "A series of recent studies have indicated that the Caveolin-1 (CAV-1) gene variant may be associated with metabolic and inflammatory markers and anthropometric measures. Furthermore, it has been shown that a plant-based dietary index (PDI) can elicit a positive impact on these metabolic markers. Therefore, we sought to examine whether PDI intakes may affect the relationship between CAV-1 (rs3807992) and metabolic factors, as well as serum inflammatory markers and anthropometric measures, in women with obesity. This current study consisted of 400 women with overweight and obesity, with a mean (SD) age of 36.67 ± 9.10 years. PDI was calculated by a food frequency questionnaire (FFQ). The anthropometric measurements and serum profiles were measured by standard protocols. Genotyping of the CAV-1(rs3807992) was conducted by the PCR-RFLP method. The following genotypic frequencies were found among the participants: GG (47.8%), AG (22.3%), and AA (2.3%). In comparison to GG homozygotes, risk-allele carriers (AA + AG) with higher PDI intake had lower ALT (P: 0.03), hs-CRP (P: 0.008), insulin (P: 0.01) and MCP-1 (P: 0.04). Furthermore, A-allele carriers were characterized by lower serum ALT (P: 0.04), AST (P: 0.02), insulin (P: 0.03), and TGF-β (P: 0.001) when had the higher following a healthful PDI compared to GG homozygote. Besides, risk-allele carriers who consumed higher unhealthful PDI had higher WC (P: 0.04), TC/HDL (P: 0.04), MCP-1 (P: 0.03), and galactin-3 (P: 0.04). Our study revealed that A-allele carriers might be more sensitive to PDI composition compared to GG homozygotes. Following a healthful PDI in A-allele carriers may be associated with improvements in metabolic and inflammatory markers and anthropometric measures."xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41598-022-12913-y"xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/author | "Mirzaei K."xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/author | "Clark C.C.T."xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/author | "Mirzababaei A."xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/author | "Abaj F."xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/author | "Bahrampour N."xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/author | "Hosseininasab D."xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/date | "2022"xsd:gYear |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/name | "Sci Rep"xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/pages | "9088"xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/title | "Interactions between Caveolin-1 polymorphism and Plant-based dietary index on metabolic and inflammatory markers among women with obesity."xsd:string |
| http://purl.uniprot.org/citations/35641515 | http://purl.uniprot.org/core/volume | "12"xsd:string |
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