http://purl.uniprot.org/citations/3576211 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3576211 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3576211 | http://www.w3.org/2000/01/rdf-schema#comment | "The nematode Caenorhabditis elegans appears to be a useful model for studying the action of volatile anesthetics. A mutant strain that is hypersensitive to the widely used anesthetic halothane was described earlier. The mutation is now shown to be an allele of unc-79. Other alleles of unc-79 are also associated with hypersensitivity to halothane. A strain with a mutation in a second gene, unc-80, is also hypersensitive to halothane. Nematodes bearing mutations in both unc-79 and unc-80 are slightly more sensitive to halothane than those bearing only one of these mutations. Mutations in a third gene, unc-9, suppress both unc-79 and unc-80. Nematodes bearing the suppressor mutations alone have normal sensitivity to halothane. These results show that sensitivity to halothane can be altered by mutations in several different genes."xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.3576211"xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.3576211"xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/author | "Sedensky M.M."xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/author | "Sedensky M.M."xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/author | "Meneely P.M."xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/author | "Meneely P.M."xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/pages | "952-954"xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/pages | "952-954"xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/title | "Genetic analysis of halothane sensitivity in Caenorhabditis elegans."xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/title | "Genetic analysis of halothane sensitivity in Caenorhabditis elegans."xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/volume | "236"xsd:string |
http://purl.uniprot.org/citations/3576211 | http://purl.uniprot.org/core/volume | "236"xsd:string |
http://purl.uniprot.org/citations/3576211 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3576211 |
http://purl.uniprot.org/citations/3576211 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3576211 |
http://purl.uniprot.org/citations/3576211 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3576211 |
http://purl.uniprot.org/citations/3576211 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3576211 |
http://purl.uniprot.org/uniprot/Q9XV66 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/3576211 |
http://purl.uniprot.org/uniprot/P42173#attribution-9E33FB75D9A4CCED78DAF730497A1CD6 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/3576211 |