Results

RDF/XMLNTriplesTurtleShow queryShare ▶
SubjectPredicateObject
http://purl.uniprot.org/citations/35987071http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/35987071http://www.w3.org/2000/01/rdf-schema#comment"

Background

Disco-interacting protein 2 C (DIP2C) has recently been reported as a new susceptibility gene for autism spectrum disorder (ASD) in a genome-wide association study.

Methods

We evaluated associations between single nucleotide polymorphisms (SNPs) of DIP2C and ASD susceptibility in a case-control study (715 ASD cases and 728 controls) from Chinese Han.

Results

We identified a significant association between SNPs (rs3740304, rs2288681, rs7088729, rs4242757, rs10795060, and rs10904083) and ASD susceptibility. Of note, rs3740304, rs2288681, and rs7088729 are positively associated with ASD under inheritance models; moreover, haplotypes with any two marker SNPs (rs3740304 [G], rs2288681 [C], rs7088729 [T], rs4242757 [C], rs10795060 [G], and rs10904083 [A]) are also significantly associated with ASD. Additionally, rs10795060 and rs10904083 are associated with "visual reaction" phenotypes of ASD.

Conclusions

DIP2C polymorphisms sort out the susceptibility and clinical phenotypes of autism spectrum disorder."xsd:string
http://purl.uniprot.org/citations/35987071http://purl.org/dc/terms/identifier"doi:10.1016/j.psychres.2022.114792"xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/author"Cheng Y."xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/author"Guo Y."xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/author"Liu Y."xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/author"Li Y."xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/author"Liu Y.'"xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/author"Sun C."xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/author"Wang H."xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/author"Zhong W."xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/author"Li Y.'"xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/author"Qiu S."xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/date"2022"xsd:gYear
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/name"Psychiatry Res"xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/pages"114792"xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/title"DIP2C polymorphisms are implicated in susceptibility and clinical phenotypes of autism spectrum disorder."xsd:string
http://purl.uniprot.org/citations/35987071http://purl.uniprot.org/core/volume"316"xsd:string
http://purl.uniprot.org/citations/35987071http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/35987071
http://purl.uniprot.org/citations/35987071http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/35987071
http://purl.uniprot.org/uniprot/#_A0A0U1RQW6-mappedCitation-35987071http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/35987071
http://purl.uniprot.org/uniprot/#_B3KWX2-mappedCitation-35987071http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/35987071
http://purl.uniprot.org/uniprot/#_Q86XV3-mappedCitation-35987071http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/35987071
http://purl.uniprot.org/uniprot/#_Q9Y2E4-mappedCitation-35987071http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/35987071
http://purl.uniprot.org/uniprot/Q86XV3http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/35987071
▶