http://purl.uniprot.org/citations/35995835 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/35995835 | http://www.w3.org/2000/01/rdf-schema#comment | "MYB and basic helix-loop-helix (bHLH) transcription factors form complexes to regulate diverse metabolic and developmental processes in plants. However, the molecular mechanisms responsible for MYB-bHLH interaction and partner selection remain unclear. Here, we report the crystal structures of three MYB-bHLH complexes (WER-EGL3, CPC-EGL3 and MYB29-MYC3), uncovering two MYB-bHLH interaction modes. WER and CPC are R2R3- and R3-type MYBs, respectively, but interact with EGL3 through their N-terminal R3 domain in a similar mode. A single amino acid of CPC, Met49, is crucial for competition with WER to interact with EGL3. MYB29, a R2R3-type MYB transcription factor, interacts with MYC3 by its C-terminal MYC-interaction motif. The WER-EGL3 and MYB29-MYC3 binding modes are widely applied among MYB-bHLH complexes in Arabidopsis and evolve independently in plants."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41477-022-01223-w"xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/author | "Li T."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/author | "Gan J."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/author | "Shen W.H."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/author | "Wu Z."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/author | "Wang B."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/author | "Luo Q."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/author | "Dong A."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/author | "Huang C.H."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/author | "Du K."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/date | "2022"xsd:gYear |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/name | "Nat Plants"xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/pages | "1108-1117"xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/title | "Structural insights into partner selection for MYB and bHLH transcription factor complexes."xsd:string |
http://purl.uniprot.org/citations/35995835 | http://purl.uniprot.org/core/volume | "8"xsd:string |
http://purl.uniprot.org/citations/35995835 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/35995835 |
http://purl.uniprot.org/citations/35995835 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/35995835 |
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http://purl.uniprot.org/uniprot/#_C0SV14-mappedCitation-35995835 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/35995835 |
http://purl.uniprot.org/uniprot/#_C0SVP6-mappedCitation-35995835 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/35995835 |
http://purl.uniprot.org/uniprot/#_O22059-mappedCitation-35995835 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/35995835 |