http://purl.uniprot.org/citations/3608987 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3608987 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3608987 | http://www.w3.org/2000/01/rdf-schema#comment | "Insecticyanin, a blue biliprotein isolated from the tobacco hornworm Manduca sexta L., is involved in insect camouflage. Its three-dimensional structure has now been solved to 2.6 A resolution using the techniques of multiple isomorphous replacement, non-crystallographic symmetry averaging about a local 2-fold rotation axis and solvent flattening. All 189 amino acids have been fitted to the electron density map. The map clearly shows that insecticyanin is a tetramer with one of its molecular 2-fold axes coincident to a crystallographic dyad. The individual subunits have overall dimensions of 44 A X 37 A X 40 A and consist primarily of an eight-stranded anti-parallel beta-barrel flanked on one side by a 4.5-turn alpha-helix. Interestingly the overall three-dimensional fold of the insecticyanin subunit shows remarkable similarity to the structural motifs of bovine beta-lactoglobulin and the human serum retinol-binding protein. The electron density attributable to the chromophore is unambiguous and shows that it is indeed the gamma-isomer of biliverdin. The biliverdin lies towards the open end of the beta-barrel with its two propionate side chains pointing towards the solvent and it adopts a rather folded conformation, much like a heme."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1987.tb02401.x"xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1987.tb02401.x"xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/author | "Holden H.M."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/author | "Holden H.M."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/author | "Rayment I."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/author | "Rayment I."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/author | "Rypniewski W.R."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/author | "Rypniewski W.R."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/author | "Law J.H."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/author | "Law J.H."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/pages | "1565-1570"xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/pages | "1565-1570"xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/title | "The molecular structure of insecticyanin from the tobacco hornworm Manduca sexta L. at 2.6-A resolution."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/title | "The molecular structure of insecticyanin from the tobacco hornworm Manduca sexta L. at 2.6-A resolution."xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/volume | "6"xsd:string |
http://purl.uniprot.org/citations/3608987 | http://purl.uniprot.org/core/volume | "6"xsd:string |
http://purl.uniprot.org/citations/3608987 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3608987 |
http://purl.uniprot.org/citations/3608987 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3608987 |