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http://purl.uniprot.org/citations/3619921http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3619921http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3619921http://www.w3.org/2000/01/rdf-schema#comment"DNA sequencing of several independent rat IGF-I cDNA clones has revealed three different 5'-untranslated region sequences which contain multiple, upstream, in-frame initiation codons. Use of these codons could generate N-terminal heterogeneity in IGF-I precursor proteins. One of these 5'-untranslated region sequences contains a 40-bp segment which is an inverted repeat of a region in the common 3'-untranslated region. The ends of the IGF-I mRNA corresponding to this cDNA could form a stable duplex structure. Such a complex could prevent ribosomal access to the AUG codons preceding the coding region for the pre-pro-IGF-I peptide, suggesting the possibility of translational regulation of this form of IGF-I mRNA. The 3'-untranslated region inverted repeat sequence also is present in human and mouse IGF-I cDNA's, and, intriguingly, is more highly conserved than the rest of the 3'-untranslated region."xsd:string
http://purl.uniprot.org/citations/3619921http://purl.org/dc/terms/identifier"doi:10.1016/0006-291X(87)90768-6"xsd:string
http://purl.uniprot.org/citations/3619921http://purl.org/dc/terms/identifier"doi:10.1016/0006-291x(87)90768-6"xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/author"Lasky S.R."xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/author"Lasky S.R."xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/author"LeRoith D."xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/author"LeRoith D."xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/author"Lowe W.L. Jr."xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/author"Roberts C.T. Jr."xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/author"Lowe W.L. Jr"xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/author"Roberts C.T. Jr"xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/date"1987"xsd:gYear
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/date"1987"xsd:gYear
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/pages"1154-1159"xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/pages"1154-1159"xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/title"Rat IGF-I cDNA's contain multiple 5'-untranslated regions."xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/title"Rat IGF-I cDNA's contain multiple 5'-untranslated regions."xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/volume"146"xsd:string
http://purl.uniprot.org/citations/3619921http://purl.uniprot.org/core/volume"146"xsd:string
http://purl.uniprot.org/citations/3619921http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3619921
http://purl.uniprot.org/citations/3619921http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3619921