| http://purl.uniprot.org/citations/36206820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/36206820 | http://www.w3.org/2000/01/rdf-schema#comment | "Hearing abnormalities are important symptoms of autism spectrum disorders (ASDs), a neurological and developmental disorder. However, the characteristics of hearing abnormalities associated with ASD during development have not been fully investigated. We found that in Shank3B knockout mice (a high-confidence mouse model of ASD), transient hearing abnormalities can be found in auditory brainstem response, auditory cortical activity, as well as acoustic startle response. More importantly, all hearing abnormalities at 4 weeks were most prominent and preceded the onset of social deficits at 6 weeks. These hearing abnormalities gradually recovered with age. In addition, analysis of ABR data at 4 weeks using Support Vector Machine (SVM) can faithfully predict the genotype of mice with an accuracy of 85.71%. These findings not only revealed hearing changes in Shank3B knockout autistic-like mice during development, but also suggested that hearing abnormalities could potentially be used as an early and effective indicator of ASD risk."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbr.2022.114149"xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/author | "Hu X."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/author | "Tu Y."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/author | "Wang X."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/author | "Zhou Y."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/author | "Yu H."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/author | "Yuan W."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/author | "Wen H."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/author | "Yan S."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/author | "Qian S."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/author | "Pang R."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/date | "2023"xsd:gYear |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/name | "Behav Brain Res"xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/pages | "114149"xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/title | "Transient hearing abnormalities precede social deficits in a mouse model of autism."xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://purl.uniprot.org/core/volume | "437"xsd:string |
| http://purl.uniprot.org/citations/36206820 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/36206820 |
| http://purl.uniprot.org/citations/36206820 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/36206820 |
| http://purl.uniprot.org/uniprot/#_A0A088DEG0-mappedCitation-36206820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36206820 |
| http://purl.uniprot.org/uniprot/#_A0A088DEG1-mappedCitation-36206820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36206820 |
| http://purl.uniprot.org/uniprot/#_A0A088DEG2-mappedCitation-36206820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36206820 |
| http://purl.uniprot.org/uniprot/#_A0A088DEG3-mappedCitation-36206820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36206820 |
| http://purl.uniprot.org/uniprot/#_A0A088DEG5-mappedCitation-36206820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36206820 |